CMD178
CMD178 is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development.
For research use only. We do not sell to patients.
- Formula: C7H7F2KOY
- Molecular Weight:850.03
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
IL-2 |
STAT5 |
FOXP3 |
CMD178 (100 mM) suppresses IL-2-induced STAT5 phosphorylation and inhibits Foxp3 expression in T cells[1].
CMD178 (100 mM) inhibits the development of Treg cells induced by IL2/sIL-2Rα signaling[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 850.03
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Formula C7H7F2KOY
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)