2. JAK/STAT Signaling Stem Cell/Wnt
  3. STAT
  4. CMD178

CMD178 is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development.

For research use only. We do not sell to patients.

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CMD178 Chemical Structure

CMD178 Chemical Structure

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Description

CMD178 is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development[1].

In Vitro

CMD178 (100 mM) suppresses IL-2-induced STAT5 phosphorylation and inhibits Foxp3 expression in T cells[1].
CMD178 (100 mM) inhibits the development of Treg cells induced by IL2/sIL-2Rα signaling[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CMD178 Related Antibodies
Molecular Weight

850.03

Formula

C7H7F2KOY
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CMD178 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CMD178CMD 178CMD-178STATlead peptidecomputationally designed peptidesFoxp3soluble IL-2RaSTAT5Treg cellsInhibitorinhibitorinhibit

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HY-P1453
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