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  2. Dentonin TFA

Dentonin TFA (Synonyms: AC-100 TFA)

Cat. No.: HY-P2633A
Handling Instructions

Dentonin TFA (AC-100 TFA) is a synthetic fragment derived from MEPE. Dentonin TFA enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin TFA has no significant effect to mature osteoblasts. Dentonin TFA can be used for the research of phosphate homeostasis and bone metabolism.

For research use only. We do not sell to patients.

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Dentonin TFA Chemical Structure

Dentonin TFA Chemical Structure

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Description

Dentonin TFA (AC-100 TFA) is a synthetic fragment derived from MEPE. Dentonin TFA enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin TFA has no significant effect to mature osteoblasts. Dentonin TFA can be used for the research of phosphate homeostasis and bone metabolism[1].

In Vitro

MEPE is a a member of the SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) family of secreted glycophosphoproteins.  MEPE  regulates bone mass and influence osteoblast activity.[1].
Dentonin TFA (3-30 μg/ml; 2-24 hours) significantly increases the numbers of cell and shows enhanced promotion of cell adhesion. However, it has no significant differences in terms of numbers of cells adhered[2].
Dentonin TFA (3-30 μg/ml; 2-24 hours) enhances osteoblast spreading, it exhibits significantly increased cell areas compared to all other treatment[2].

Molecular Weight

2652.61

Formula

C₁₀₉H₁₆₁F₃N₃₀O₄₄

Sequence Shortening

TDLQERGDNDISPFSGDGQPFKD

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

DentoninAC-100AC100AC 100OthersOsteogenesis Inducercell adhesionosteoblastfocal complex formationInhibitorinhibitorinhibit

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Dentonin TFA
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HY-P2633A
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