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APC 366 TFA 

Cat. No.: HY-105999B
Handling Instructions

APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic diseases.

For research use only. We do not sell to patients.

APC 366 TFA Chemical Structure

APC 366 TFA Chemical Structure

CAS No. : 2421110-28-1

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Description

APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic diseases[1].

IC50 & Target

mast cell tryptase[1]

In Vivo

APC 366 (TFA) (5 mg/kg/0.1 ml; s.c.) reduces the eosinophil recruitment induced by PAR-2 activating peptide[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male BALB/c mice (18–25 g)[1]
Dosage: 5 mg/kg/0.1 ml
Administration: S.c.
Result: Reduced the eosinophil recruitment induced by PAR-2 activating peptide.
Molecular Weight

554.52

Formula

C24H29F3N6O6

CAS No.
SMILES

OC(C(F)(F)F)=O.OC1=C(C(N[[email protected]@H](CCCNC(N)=N)C(N2[[email protected]@H](CCC2)C(N)=O)=O)=O)C=CC3=C1C=CC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
APC 366 TFA
Cat. No.:
HY-105999B
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