1. Neuronal Signaling
    Stem Cell/Wnt
  2. Notch
  3. Jagged-1 (188-204) (TFA)

Jagged-1 (188-204) (TFA) 

Cat. No.: HY-P1846A Purity: 99.39%
COA Handling Instructions

Jagged-1 (188-204) TFA is a fragment of the Jagged-1 (JAG-1) protein with Notch agonist activity. JAG-1 is a Notch ligand highly expressed in cultured and primary multiple myeloma (MM) cells. JAG-1 induces maturation of monocyte-derived human dendritic cells.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Jagged-1 (188-204) (TFA) Chemical Structure

Jagged-1 (188-204) (TFA) Chemical Structure

Size Price Stock Quantity
1 mg USD 250 In-stock
Estimated Time of Arrival: December 31
5 mg USD 450 In-stock
Estimated Time of Arrival: December 31
10 mg USD 750 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Jagged-1 (188-204) (TFA):

Top Publications Citing Use of Products

2 Publications Citing Use of MCE Jagged-1 (188-204) (TFA)

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Jagged-1 (188-204) TFA is a fragment of the Jagged-1 (JAG-1) protein with Notch agonist activity. JAG-1 is a Notch ligand highly expressed in cultured and primary multiple myeloma (MM) cells. JAG-1 induces maturation of monocyte-derived human dendritic cells[1][2][3].

In Vitro

Jagged-1 (188-204) is part of the DSL region, and highly conserved between human Jagged-1 and Jagged-2[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

2221.42

Formula

C95H128F3N25O28S3

Sequence Shortening

CDDYYYGFGCNKFCRPR

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (22.51 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4502 mL 2.2508 mL 4.5016 mL
5 mM 0.0900 mL 0.4502 mL 0.9003 mL
10 mM 0.0450 mL 0.2251 mL 0.4502 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: 99.39%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
Jagged-1 (188-204) (TFA)
Cat. No.:
HY-P1846A
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