FN-439 TFA
Based on 1 Customer Validation
FN-439 TFA is a selective collagenase-1 inhibitor. FN-439 TFA inhibits collagenase-1 with an IC50 value of 1 μM. FN-439 TFA can be used for the research of cancer and inflammation.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.65%
- Formel: C25H35F3N6O8
- Molecular Weight:604.58
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Speicherung:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
Chemical Information
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Appearance Solid
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Molecular Weight 604.58
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Formel C25H35F3N6O8
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Color White to off-white
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SMILES
OC(C(F)(F)F)=O.ONC([C@@H](C)NC([C@@H](CC(C)C)NC([C@H]1N(CCC1)C(CNC(C2=CC=C(C=C2)N)=O)=O)=O)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Lösungsmittel & Löslichkeit
In Vitro:
H2O : 250 mg/mL (413.51 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. U Benbow, et al. Human breast cancer cells activate procollagenase-1 and invade type I collagen: invasion is inhibited by all-trans retinoic acid. Clin Exp Metastasis. 1999 May;17(3):231-8. [Content Brief]
[2]. H Anan, et al. Effects of a combination of an antibacterial agent (ofloxacin) and a collagenase inhibitor (FN-439) on the healing of rat periapical lesions. J Endod. 1996 Dec;22(12):668-73. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.6540 mL | 8.2702 mL | 16.5404 mL | 41.3510 mL |
| 5 mM | 0.3308 mL | 1.6540 mL | 3.3081 mL | 8.2702 mL | |
| 10 mM | 0.1654 mL | 0.8270 mL | 1.6540 mL | 4.1351 mL | |
| 15 mM | 0.1103 mL | 0.5513 mL | 1.1027 mL | 2.7567 mL | |
| 20 mM | 0.0827 mL | 0.4135 mL | 0.8270 mL | 2.0676 mL | |
| 25 mM | 0.0662 mL | 0.3308 mL | 0.6616 mL | 1.6540 mL | |
| 30 mM | 0.0551 mL | 0.2757 mL | 0.5513 mL | 1.3784 mL | |
| 40 mM | 0.0414 mL | 0.2068 mL | 0.4135 mL | 1.0338 mL | |
| 50 mM | 0.0331 mL | 0.1654 mL | 0.3308 mL | 0.8270 mL | |
| 60 mM | 0.0276 mL | 0.1378 mL | 0.2757 mL | 0.6892 mL | |
| 80 mM | 0.0207 mL | 0.1034 mL | 0.2068 mL | 0.5169 mL | |
| 100 mM | 0.0165 mL | 0.0827 mL | 0.1654 mL | 0.4135 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
FN-439 TFA Related Classifications
HY-100210A Related Classifications
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