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Cat. No.: HY-153096A

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OICR12694 TFA

(Synonyms: JNJ-65234637 TFA)

OICR12694 (JNJ-65234637) TFA is an orally active inhibitor of B cell lymphoma 6 (BCL6).

For research use only. We do not sell to patients.

CAS No.: 2360625-98-3
Formula: C₂₉H₂₈ClF₃N₈O₄.xC₂HF₃O₂

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

OICR12694 TFA Chemical Structure

CAS No.: 2360625-98-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

OICR12694 (JNJ-65234637) TFA is an orally active inhibitor of B cell lymphoma 6 (BCL6)^[1].

IC₅₀ & Target

B cell lymphoma 6 (BCL6)^[1]

All Bcl-2 Family Isoforms :

Chemical Information

CAS No. 2360625-98-3
Formula C₂₉H₂₈ClF₃N₈O₄.xC₂HF₃O₂
SMILES

O=C1C2=C(N=C3N1CCC3)N(CC(NC4=C(Cl)C(F)=NC(N5[C@H](CN(CC5)C)C)=C4)=O)C=C2C6=CC(C(N)=O)=C(C(F)=C6F)O.O=C(O)C(F)(F)F.[x]
Synonyms

JNJ-65234637 TFA
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mamai A, et al. Discovery of OICR12694: A Novel, Potent, Selective, and Orally Bioavailable BCL6 BTB Inhibitor. ACS Med Chem Lett. 2023 Jan 12;14(2):199-210. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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OICR12694 TFA

All Bcl-2 Family Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

OICR12694 TFA Related Classifications

HY-153096A Related Classifications