PSMA targeting peptide TFA
Based on 1 publication(s) in Google Scholar
PSMA targeting peptide (PSMA-1) TFA is a PSMA-binding peptide that selectively binds to the PSMA receptor on prostate cancer cells and acts as a peptide-based siRNA delivery system by complexing and releasing siRNA. PSMA targeting peptide TFA can be used in research on prostate cancer.
For research use only. We do not sell to patients.
- Purity : 98.54%
- Formula: C70H122N24O19.xC2HF3O2
- Molecular Weight:1603.87 (free base)
-
Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) PSMA targeting peptide TFA
More
Biological Activity
Description
IC50 & Target
IC50: PSMA[1]
In Vitro
PSMA-1-R6 forms large, anionic, polydisperse complexes with siRNA, with a zeta potential of -2.16 mV, effective diameters of 1450 nm (aggregates) and 878 nm (individual particles), and a tendency to aggregate[1].
PSMA-1-R6 (5 min; 1 week), when complexed with siRNA, formed large, polydisperse aggregated particles with an average size 200-300 nm larger than that of the siRNA:Trans-IT X2 control complexes[1].
PSMA-1-R6 peptide (625 pmol; 48 h) failed to mediate functional siRNA delivery and GRP78 knockdown at both mRNA and protein levels in both LNCaP and PC3 cell lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Appearance Solid
-
Molecular Weight 1603.87 (free base)
-
Formula C70H122N24O19.xC2HF3O2
-
Color White to off-white
-
Synonyms
PSMA-1 TFA
-
Sequence
Gly-Arg-Phe-Leu-Thr-Gly-Gly-Thr-Gly-Arg-Leu-Leu-Arg-Ile-Ser
-
Sequence Shortening
GRFLTGGTGRLLRIS
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
J Control Release
Targeting polyamine metabolism induces oxidative/carbonyl stress to reinvigorate antitumor immunity in prostate cancer. [Abstract]2025 Sep 30;388(Pt 1):114283. PMID: 41038348
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (Need ultrasonic)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PSMA targeting peptide TFA Related Classifications
HY-P10055A Related Classifications
Powered by Bioz