2. Metabolic Enzyme/Protease Membrane Transporter/Ion Channel
  3. Endogenous Metabolite Potassium Channel
  4. L-Palmitoylcarnitine TFA

L-Palmitoylcarnitine TFA 

Cat. No.: HY-113147B Purity: ≥98.0%
COA Handling Instructions

L-Palmitoylcarnitine TFA, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine TFA inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2.

For research use only. We do not sell to patients.

L-Palmitoylcarnitine TFA Chemical Structure

L-Palmitoylcarnitine TFA Chemical Structure

Size Price Stock Quantity
5 mg USD 51 In-stock
10 mg USD 80 In-stock
50 mg USD 280 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of L-Palmitoylcarnitine TFA:

L-Palmitoylcarnitine TFA Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE L-Palmitoylcarnitine TFA

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

L-Palmitoylcarnitine TFA, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine TFA inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1].

IC50 & Target[1]

Human Endogenous Metabolite

 

In Vitro

L-Palmitoylcarnitine (1 µM) inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2. L-Palmitoylcarnitine simultaneously enhances the ATP sensitivity of the channel (IC50 fell from 62 to 30 µM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Palmitoylcarnitine TFA Related Antibodies
Molecular Weight

513.63

Appearance

Solid

Formula

C25H46F3NO6
SMILES

CCCCCCCCCCCCCCCC(O[C@H](CC([O-])=O)C[N+](C)(C)C)=O.OC(C(F)(F)F)=O
Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (194.69 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9469 mL 9.7346 mL 19.4693 mL
5 mM 0.3894 mL 1.9469 mL 3.8939 mL
10 mM 0.1947 mL 0.9735 mL 1.9469 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (4.87 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (4.87 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.5 mg/mL (4.87 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation
References
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L-Palmitoylcarnitine TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

L-PalmitoylcarnitineEndogenous MetabolitePotassium ChannelKcsAfattyacidmetaboliteischaemialipidInhibitorinhibitorinhibit

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Cat. No.:
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