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  2. Xenopsin TFA

Xenopsin TFA 

Cat. No.: HY-P0253A
Handling Instructions

Xenopsin TFA, a neurotensin-like octapeptide from Xenopus laevis skin. Xenopsin TFA is an inhibitor of Tetragastrin stimulated gastric acid secretion.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Xenopsin TFA Chemical Structure

Xenopsin TFA Chemical Structure

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Other Forms of Xenopsin TFA:

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Description

Xenopsin TFA, a neurotensin-like octapeptide from Xenopus laevis skin[1]. Xenopsin TFA is an inhibitor of Tetragastrin stimulated gastric acid secretion[2].

In Vitro

Xenopsin is a biologically active octapeptide found in skin extracts from Xenopus laevis[1]. Xenopsin produces a significant inhibition of tetragastrin-stimulated gastric acid output[2].

Molecular Weight

1094.19

Formula

C₄₉H₇₄F₃N₁₃O₁₂

Sequence

{Glp}-Gly-Lys-Arg-Pro-Trp-Ile-Leu

Sequence Shortening

{Glp}-GKRPWIL

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

XenopsinOthersNeurotensinOctapeptidegastricacidsecretionInhibitorinhibitorinhibit

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Xenopsin TFA
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HY-P0253A
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