2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Angiotensinogen (1-14), human TFA

Angiotensinogen (1-14), human TFA is a fragment of the renin substrate angiotensinogen. Angiotensinogen is naturally occurring substrate for renin and a precursor for all angiotensin peptides.

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Custom Peptide Synthesis

Angiotensinogen (1-14), human TFA Chemical Structure

Angiotensinogen (1-14), human TFA Chemical Structure

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Angiotensinogen (1-14), human TFA Related Antibodies

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Description

Angiotensinogen (1-14), human TFA is a fragment of the renin substrate angiotensinogen. Angiotensinogen is naturally occurring substrate for renin and a precursor for all angiotensin peptides[1][2].

IC50 & Target[1][2]

Human Endogenous Metabolite

 

In Vitro

Angiotensinogen (AGT) is the only precursor of all angiotensin peptides. Human AGT has 485 amino acids, including a 33 amino-acid signal peptide. The 10 N-terminal amino acids are cleaved by renin to provide angiotensin I (AngI), which is the source for an array of active angiotensin peptides[1].
Angiotensinogen isolated from most species is cleaved by human renin. Synthetic peptides containing the N-terminal amino-acid sequence of angiotensinogen were renin substrates[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Angiotensinogen (1-14), human TFA Related Antibodies
Molecular Weight

1760.01 (free acid)

Formula

C83H122N24O19.xC2HF3O2
Sequence Shortening

DRVYIHPFHLVIHN
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Angiotensinogen (1-14), human TFA Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Angiotensinogen (1-14), humanEndogenous MetabolitefragmentreninsubstrateangiotensinogenprecursorangiotensinpeptidesInhibitorinhibitorinhibit

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