Biphalin TFA
Biphalin TFA, a BBB-penetrable opioid peptide analog, contains two active enkephalin pharmacophores. Biphalin TFA has high affinity for opioid receptors. Biphalin TFA shows analgesic effect in acute, neuropathic, and chronic animal pain models. Biphalin TFA is also an antiviral, antiproliferative, anti-inflammatory, and neuroprotective agent.
For research use only. We do not sell to patients.
- CAS No.: 126872-95-5
- Formula: C46H56N10O10·xC2HF3O2
- Molecular Weight:909.00 (free base)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Opioid Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 126872-95-5
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Molecular Weight 909.00 (free base)
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Formula C46H56N10O10·xC2HF3O2
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Sequence
Tyr-{dAla}-Gly-Phe-NH2 (covalent bridge:Phe-Phe, dimer)
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Sequence Shortening
Y-{D-Ala}-GF-NH2 (covalent bridge:Phe-Phe, dimer)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. T J Abbruscato, et al. Blood-to-central nervous system entry and stability of biphalin, a unique double-enkephalin analog, and its halogenated derivatives. J Pharmacol Exp Ther. 1996, 276,3. [Content Brief]
[2]. Redkiewicz P, et al. Biphalin-A Potent Opioid Agonist-As a Panacea for Opioid System-Dependent Pathophysiological Diseases? Int J Mol Sci. 2021 Oct 21;22(21):11347. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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