[Sar9,Met(O2)11]-Substance P TFA
Based on 1 Customer Validation
[Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK1 receptor selective agonist.
For research use only. We do not sell to patients.
- Purity: 98.58%
- CAS No.: 2828433-10-7
- Formula: C66H101F3N18O17S
- Molecular Weight:1507.68
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
![[Sar9,Met(O2)11]-Substance P TFA Chemical Structure](https://file.medchemexpress.com/product_pic/hy-p1012a.gif "Click to View [Sar9,Met(O2)11]-Substance P TFA Chemical Structure")
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-P0197A
Neurokinin A TFA
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HY-P1492
Substance P (7-11)
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HY-P1485A
Substance P(1-7) TFA
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![[Sar9] Substance P](https://file.medchemexpress.com/product_pic/hy-p1738.gif)
HY-P1738
[Sar9] Substance P
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HY-P1485
Substance P(1-7)
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HY-P0242A
Neurokinin B TFA
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HY-P0201A
Substance P TFA
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HY-14407A
Fosaprepitant dimeglumine
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HY-P2546
Biotin-Substance P
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HY-109171
Elinzanetant
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HY-P1494
Substance P (1-9)
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HY-16732
Tradipitant
Biological Activity
NK1 receptor[1]
[Sar9,Met(O2)11]-Substance P and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P is the sole to produce grooming[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2828433-10-7
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Appearance Solid
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Molecular Weight 1507.68
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Formula C66H101F3N18O17S
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Color White to off-white
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Sequence
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-{Sar}-Leu-Met[O2]-NH2
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Sequence Shortening
RPKPQQFF-{Sar}-LM[O2]-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 100 mg/mL (66.33 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 50 mg/mL (33.16 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.6633 mL | 3.3164 mL | 6.6327 mL | 16.5818 mL |
| 5 mM | 0.1327 mL | 0.6633 mL | 1.3265 mL | 3.3164 mL | |
| 10 mM | 0.0663 mL | 0.3316 mL | 0.6633 mL | 1.6582 mL | |
| 15 mM | 0.0442 mL | 0.2211 mL | 0.4422 mL | 1.1055 mL | |
| 20 mM | 0.0332 mL | 0.1658 mL | 0.3316 mL | 0.8291 mL | |
| 25 mM | 0.0265 mL | 0.1327 mL | 0.2653 mL | 0.6633 mL | |
| 30 mM | 0.0221 mL | 0.1105 mL | 0.2211 mL | 0.5527 mL | |
| 40 mM | 0.0166 mL | 0.0829 mL | 0.1658 mL | 0.4145 mL | |
| 50 mM | 0.0133 mL | 0.0663 mL | 0.1327 mL | 0.3316 mL | |
| 60 mM | 0.0111 mL | 0.0553 mL | 0.1105 mL | 0.2764 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
[Sar9,Met(O2)11]-Substance P TFA Related Classifications
HY-P1012A Related Classifications
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