Angiogenin (108-122) (TFA)

Name: Angiogenin (108-122) (TFA)
Brand: MedChemExpress
SKU: HY-P1516A
Rating: 4.5 (1 reviews)

Cat. No.: HY-P1516A Purity: 98.70%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Angiogenin (108-122) TFA is an angiogenin peptide.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Angiogenin (108-122) (TFA) Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 55	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 90	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 180	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Angiogenin (108-122) TFA is an angiogenin peptide.

In Vitro

Angiogenin (108-122) effects on the ribonucleolytic activity of angiogenin using tRNA as substrate with 39% inhibition^[1]. Angiogenin (108-122) acts as a therapeutic agent for the prophylaxis and/or treatment of cancer, an infectious disease, a fibrotic disease, an inflammatory disease, a neurodegenerative disease, an autoimmune disease, or a heart and vascular disease^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1895.00

Formula

C₈₀H₁₂₆F₃N₂₅O₂₅

Appearance

Solid

Color

White to off-white

Sequence

Glu-Asn-Gly-Leu-Pro-Val-His-Leu-Asp-Gln-Ser-Ile-Phe-Arg-Arg

Sequence Shortening

ENGLPVHLDQSIFRR

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 50 mg/mL (26.39 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.5277 mL	2.6385 mL	5.2770 mL
5 mM	0.1055 mL	0.5277 mL	1.0554 mL
10 mM	0.0528 mL	0.2639 mL	0.5277 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 25 mg/mL (13.19 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.70%

Select Batch:

Data Sheet (269 KB) SDS (251 KB)

COA (240 KB) LCMS (139 KB)

Handling Instructions (2659 KB)

References

[1]. Rybak SM, et al. C-terminal angiogenin peptides inhibit the biological and enzymatic activities of angiogenin. Biochem Biophys Res Commun. 1989 Jul 14;162(1):535-43. [Content Brief]

[2]. Dorian Bevec, et al. Therapeutic uses of angiogenin 108-122 and gluten exorphin a5. WO2009043455A2.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	0.5277 mL	2.6385 mL	5.2770 mL	13.1926 mL
	5 mM	0.1055 mL	0.5277 mL	1.0554 mL	2.6385 mL
	10 mM	0.0528 mL	0.2639 mL	0.5277 mL	1.3193 mL
	15 mM	0.0352 mL	0.1759 mL	0.3518 mL	0.8795 mL
	20 mM	0.0264 mL	0.1319 mL	0.2639 mL	0.6596 mL
	25 mM	0.0211 mL	0.1055 mL	0.2111 mL	0.5277 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Angiogenin (108-122) (TFA)OthersInhibitorinhibitorinhibit

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Angiogenin (108-122) (TFA)

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