1. GPCR/G Protein
    Neuronal Signaling
  2. mAChR
    Adrenergic Receptor
  3. G-Protein antagonist peptide TFA

G-Protein antagonist peptide TFA 

Cat. No.: HY-P1376A Purity: 97.35%
Handling Instructions

G-Protein antagonist peptide TFA is a truncated substance P-related peptide, competes with receptor for G protein binding. G-Protein antagonist peptide TFA inhibits the activation of Gi or Go by M2 muscarinic cholinergic receptor (M2 mAChR) or of Gs by beta-adrenergic receptor in the reconstituted phospholipid vesicles, assayed by receptor-promoted GTP hydrolysis.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

G-Protein antagonist peptide TFA Chemical Structure

G-Protein antagonist peptide TFA Chemical Structure

Size Price Stock Quantity
1 mg USD 150 In-stock
Estimated Time of Arrival: December 31
5 mg USD 400 In-stock
Estimated Time of Arrival: December 31
10 mg USD 640 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

G-Protein antagonist peptide TFA is a truncated substance P-related peptide, competes with receptor for G protein binding. G-Protein antagonist peptide TFA inhibits the activation of Gi or Go by M2 muscarinic cholinergic receptor (M2 mAChR) or of Gs by beta-adrenergic receptor in the reconstituted phospholipid vesicles, assayed by receptor-promoted GTP hydrolysis[1].

Molecular Weight

1207.28

Formula

C₅₉H₆₅F₃N₁₂O₁₁S

Sequence

{Glp}-Gln-Trp-Phe-Trp-Trp-Met-NH2

Sequence Shortening

{Glp}QWFWWM-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (41.42 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8283 mL 4.1415 mL 8.2831 mL
5 mM 0.1657 mL 0.8283 mL 1.6566 mL
10 mM 0.0828 mL 0.4142 mL 0.8283 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (2.07 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
G-Protein antagonist peptide TFA
Cat. No.:
HY-P1376A
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