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Cat. No.: HY-P1249A

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Neuropeptide SF(mouse,rat) TFA

Neuropeptide SF (mouse,rat) TFA is a potent neuropeptide FF receptor agonist with K_i values are 48.4 nM and 12.1 nM for NPFF1 and NPFF2, respectively. Neuropeptide SF TFA increases the amplitude of the sustained current of heterologously expressed acid sensing ion channel 3 (ASIC3) .

For research use only. We do not sell to patients.

Formula: C₄₂H₆₆F₃N₁₃O₁₂
Molecular Weight:1002.05

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Neuropeptide SF(mouse,rat) TFA Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

Neuropeptide FF Receptor Agonist

All Neuropeptide Y Receptor Isoforms :

Chemical Information

Molecular Weight 1002.05
Formula C₄₂H₆₆F₃N₁₃O₁₂
Sequence

Ser-Leu-Ala-Ala-Pro-Gln-Arg-Phe-NH2
Sequence Shortening

SLAAPQRF-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Miklós Jászberényi, et al. The actions of neuropeptide SF on the hypothalamic-pituitary-adrenal axis and behavior in rats.Regul Pept. 2014 Jan 10;188:46-51. [Content Brief]

[2]. K Jhamandas, et al. Facilitation of spinal morphine analgesia in normal and morphine tolerant animals by neuropeptide SF and related peptides.Peptides. 2006 May;27(5):953-63. [Content Brief]

[3]. C Gouardères, et al. Quantitative autoradiographic distribution of NPFF1 neuropeptide FF receptor in the rat brain and comparison with NPFF2 receptor by using [125I]YVP and [(125I]EYF as selective radioligands. Neuroscience. 2002;115(2):349-61. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Neuropeptide SF(mouse,rat) TFA

All Neuropeptide Y Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Neuropeptide SF(mouse,rat) TFA Related Classifications

HY-P1249A Related Classifications