Calcineurin autoinhibitory peptide TFA

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Calcineurin autoinhibitory peptide TFA is a selective inhibitor of Ca²⁺/calmodulin-dependent protein phosphatase (calcineurin), with an IC₅₀ of ~10 μM. Calcineurin autoinhibitory peptide TFA could protect neurons from excitatory neuronal death.

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Calcineurin autoinhibitory peptide TFA Estructura química

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Other In-stock Forms of Calcineurin autoinhibitory peptide TFA:

Calcineurin autoinhibitory peptide

Other Forms of Calcineurin autoinhibitory peptide TFA:

Calcineurin autoinhibitory peptide In-stock

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Descripciòn	Calcineurin autoinhibitory peptide TFA is a selective inhibitor of Ca²⁺/calmodulin-dependent protein phosphatase (calcineurin), with an IC₅₀ of ~10 μM. Calcineurin autoinhibitory peptide TFA could protect neurons from excitatory neuronal death^[1]^[2].
IC₅₀ & Target	IC50: ~10 μM (calcineurin)^[1]
Fòrmula	C₁₂₄H₂₀₅N₃₉O₃₉S₂.xC₂HF₃O₂
Sequence Shortening	ITSFEEAKGLDRINERMPPRRDAMP
Envío	Room temperature in continental US; may vary elsewhere.
Almacenamiento	Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación	Ficha de datos (263 KB) Instrucciones de manejo (2659 KB)
Referencias	[1]. Hashimoto Y, et, al. Identification of an autoinhibitory domain in calcineurin. J Biol Chem. 1990 Feb 5; 265(4): 1924-7. [Content Brief] [2]. Terada H, et, al. Inhibition of excitatory neuronal cell death by cell-permeable calcineurin autoinhibitory peptide. J Neurochem. 2003 Dec; 87(5): 1145-51. [Content Brief]