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  3. Fibrinopeptide B, human TFA

Fibrinopeptide B, human TFA  (Synonyms: FPB,human TFA)

Cat. No.: HY-P1493A Purity: 99.11%
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Fibrinopeptide B, human TFA (FPB,human TFA), human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin.

For research use only. We do not sell to patients.

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Fibrinopeptide B, human TFA Chemical Structure

Fibrinopeptide B, human TFA Chemical Structure

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1 mg USD 90 In-stock
5 mg USD 220 In-stock
10 mg USD 330 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Fibrinopeptide B, human TFA:

Fibrinopeptide B, human TFA Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

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Description

Fibrinopeptide B, human TFA (FPB,human TFA), human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin[1].

In Vitro

Fibrinopeptide B, human is released from the amino-terminus of the B 3-chains of fibrinogen by thrombin. Fibrinopeptide B, human (hFpB, 10 nM) causes directed cell migration of neutrophils (PMN), and fibroblasts. Fibrinopeptide B, human also possesses potent chemotactic activity relative to human complement (C5a), leukotriene B4 (LTB4), and formyl-methionylleucyl-phenylalanine (fMLP), and for fibroblasts its chemotactic activity is comparable to that of platelet-derived growth factor. However, Fibrinopeptide B, human is not chemotactic for monocytes, and shows no interaction with PMN receptor for C5a, LTB4, or fMLP[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fibrinopeptide B, human TFA Related Antibodies
Molecular Weight

1666.58

Formula

C68H94F3N19O27
Appearance

Solid

Color

White to off-white

Sequence

{Glp}-Gly-Val-Asn-Asp-Asn-Glu-Glu-Gly-Phe-Phe-Ser-Ala-Arg
Sequence Shortening

{Glp}-GVNDNEEGFSAR
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 1.25 mg/mL (0.75 mM; Need ultrasonic)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 2 mg/mL (1.20 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fibrinopeptide B, humanFPB,humanOthersinflammatoryepitopeequilibrationfibrinphysiologicthrombinInhibitorinhibitorinhibit

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