6H05 TFA
Based on 1 Customer Validation
6H05 TFA is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C).
For research use only. We do not sell to patients.
- Purity: 99.02%
- CAS No.: 2061344-88-3
- Formula: C22H31ClF3N3O4S3
- Molecular Weight:590.14
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 2061344-88-3
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Appearance Solid
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Molecular Weight 590.14
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Formula C22H31ClF3N3O4S3
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Color White to off-white
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SMILES
O=C(C1CCN(C(CSC2=CC=C(Cl)C=C2)=O)CC1)NCCSSCCN(C)C.O=C(O)C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 100 mg/mL (169.45 mM)
DMSO : ≥ 51 mg/mL (86.42 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 1.6945 mL | 8.4726 mL | 16.9451 mL | 42.3628 mL |
| 5 mM | 0.3389 mL | 1.6945 mL | 3.3890 mL | 8.4726 mL | |
| 10 mM | 0.1695 mL | 0.8473 mL | 1.6945 mL | 4.2363 mL | |
| 15 mM | 0.1130 mL | 0.5648 mL | 1.1297 mL | 2.8242 mL | |
| 20 mM | 0.0847 mL | 0.4236 mL | 0.8473 mL | 2.1181 mL | |
| 25 mM | 0.0678 mL | 0.3389 mL | 0.6778 mL | 1.6945 mL | |
| 30 mM | 0.0565 mL | 0.2824 mL | 0.5648 mL | 1.4121 mL | |
| 40 mM | 0.0424 mL | 0.2118 mL | 0.4236 mL | 1.0591 mL | |
| 50 mM | 0.0339 mL | 0.1695 mL | 0.3389 mL | 0.8473 mL | |
| 60 mM | 0.0282 mL | 0.1412 mL | 0.2824 mL | 0.7060 mL | |
| 80 mM | 0.0212 mL | 0.1059 mL | 0.2118 mL | 0.5295 mL | |
| H2O | 100 mM | 0.0169 mL | 0.0847 mL | 0.1695 mL | 0.4236 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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