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  3. 6H05

6H05 

Cat. No.: HY-12408
Handling Instructions

6H05 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C).

For research use only. We do not sell to patients.

6H05 Chemical Structure

6H05 Chemical Structure

CAS No. : 1469338-01-9

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Description

6H05 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C). IC50 value: Target: K-Ras G12C 6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras [1]. 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors [2].

IC50 & Target[1]

K-Ras(G12C)

 

Molecular Weight

476.12

Formula

C₂₀H₃₀ClN₃O₂S₃

CAS No.

1469338-01-9

SMILES

O=C(C1CCN(C(CSC2=CC=C(Cl)C=C2)=O)CC1)NCCSSCCN(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

6H05RasInhibitorinhibitorinhibit

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6H05
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HY-12408
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