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  2. Fibrinogen-Binding Peptide TFA

Fibrinogen-Binding Peptide TFA 

Cat. No.: HY-P1741A Purity: 98.66%
COA Handling Instructions

Fibrinogen-Binding Peptide TFA (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide TFA binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Fibrinogen-Binding Peptide TFA Chemical Structure

Fibrinogen-Binding Peptide TFA Chemical Structure

Size Price Stock Quantity
1 mg USD 50 In-stock
5 mg USD 120 In-stock
10 mg USD 185 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Fibrinogen-Binding Peptide TFA:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Fibrinogen-Binding Peptide TFA

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Fibrinogen-Binding Peptide TFA (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide TFA binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin[1].

Molecular Weight

679.64

Formula

C27H40F3N7O10

Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (367.84 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4714 mL 7.3568 mL 14.7137 mL
5 mM 0.2943 mL 1.4714 mL 2.9427 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.4714 mL 7.3568 mL 14.7137 mL 36.7842 mL
5 mM 0.2943 mL 1.4714 mL 2.9427 mL 7.3568 mL
10 mM 0.1471 mL 0.7357 mL 1.4714 mL 3.6784 mL
15 mM 0.0981 mL 0.4905 mL 0.9809 mL 2.4523 mL
20 mM 0.0736 mL 0.3678 mL 0.7357 mL 1.8392 mL
25 mM 0.0589 mL 0.2943 mL 0.5885 mL 1.4714 mL
30 mM 0.0490 mL 0.2452 mL 0.4905 mL 1.2261 mL
40 mM 0.0368 mL 0.1839 mL 0.3678 mL 0.9196 mL
50 mM 0.0294 mL 0.1471 mL 0.2943 mL 0.7357 mL
60 mM 0.0245 mL 0.1226 mL 0.2452 mL 0.6131 mL
80 mM 0.0184 mL 0.0920 mL 0.1839 mL 0.4598 mL
100 mM 0.0147 mL 0.0736 mL 0.1471 mL 0.3678 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Fibrinogen-Binding Peptide TFA
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HY-P1741A
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