1. Apoptosis
  2. TNF Receptor
  3. LEESGGGLVQPGGSMK TFA

LEESGGGLVQPGGSMK TFA 

Cat. No.: HY-P3149A
Handling Instructions

LEESGGGLVQPGGSMK TFA, a proteolysis peptide, is a component of Infliximab. LEESGGGLVQPGGSMK TFA can be used for quantitative analysis of Infliximab. Infliximab is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

LEESGGGLVQPGGSMK TFA Chemical Structure

LEESGGGLVQPGGSMK TFA Chemical Structure

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Description

LEESGGGLVQPGGSMK TFA, a proteolysis peptide, is a component of Infliximab. LEESGGGLVQPGGSMK TFA can be used for quantitative analysis of Infliximab. Infliximab is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α[1].

In Vitro

The anti-TNF antibodies blocking the action of TNF alpha revolutionized therapy of TNF-related diseases such as Inflammatory Bowel Disease, lupus, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis. By neutralizing TNF activity, anti-TNF antibodies promote mucosal healing and induce long-term remissions in vivo. The main anti-TNF antibodies that are currently authorized encompass Infliximab, Etanercept, Adalimumab, Certolizumab and Golimumab[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1659.73

Formula

C₆₆H₁₀₉F₃N₁₈O₂₆S

Sequence Shortening

LEESGGGLVQPGGSMK

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

LEESGGGLVQPGGSMKTNF ReceptorTumor Necrosis Factor ReceptorTNFRproteolysispeptideInfliximabTNF-αInhibitorinhibitorinhibit

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LEESGGGLVQPGGSMK TFA
Cat. No.:
HY-P3149A
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