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  2. Arg-Gly-Glu-Ser(TFA)

Arg-Gly-Glu-Ser(TFA) 

Cat. No.: HY-P0309A Purity: 98.22%
Handling Instructions

Arg-Gly-Glu-Ser(TFA) is a RGD-related peptide and a control for the RGDS ihibitory activity on fibrinogen binding to activated platelets.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Arg-Gly-Glu-Ser(TFA) Chemical Structure

Arg-Gly-Glu-Ser(TFA) Chemical Structure

Size Price Stock Quantity
10 mM * 1 mL USD 136 In-stock
Estimated Time of Arrival: December 31
2 mg USD 50 In-stock
Estimated Time of Arrival: December 31
5 mg USD 110 In-stock
Estimated Time of Arrival: December 31
10 mg USD 190 In-stock
Estimated Time of Arrival: December 31
25 mg USD 390 In-stock
Estimated Time of Arrival: December 31
50 mg USD 690 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Arg-Gly-Glu-Ser(TFA):

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Description

Arg-Gly-Glu-Ser(TFA) is a RGD-related peptide and a control for the RGDS ihibitory activity on fibrinogen binding to activated platelets.

In Vivo

Arg-Gly-Glu-Ser (5 mg/kg) in combination with LPS or saline + RGDS does not affect neutrophil and macrophage cell numbers and has no effect on protein accumulation compared with LPS- or saline-treated mice, respectively[1].

Molecular Weight

561.47

Formula

C₁₈H₃₀F₃N₇O₁₀

Sequence

Arg-Gly-Glu-Ser

Sequence Shortening

RGES

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 20 mg/mL (35.62 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7810 mL 8.9052 mL 17.8104 mL
5 mM 0.3562 mL 1.7810 mL 3.5621 mL
10 mM 0.1781 mL 0.8905 mL 1.7810 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Animal Administration
[1]

Mice[1]
Mouse pharyngeal aspiration is performed in the assay. Animals are anesthetized with a mixture of ketamine and xylazine (45 mg/kg and 8 mg/kg, i.p., respectively). Test solution (30 μL) containing LPS (1.5 mg/kg) is placed posterior in the throat and aspirated into the lungs. Control mice are administrated sterile saline (0.9% NaCl). Animals are administered with RGDS or Arg-Gly-Glu-Ser peptide (1, 2.5 or 5 mg/kg, i.p.) once one hour before LPS treatment and sacrificed 4 h post-LPS. Animals are also administered RGDS or Arg-Gly-Glu-Ser peptide (5 mg/kg, i.p.) once at different time points (1 h before or 2 h after LPS treatment) and sacrificed 24 h post-LPS. In addition, animals are administered with αvβ3-blocking mAbs, anti-αv, or anti-β3 (5 mg/kg, i.p.) once 1 h before and sacrificed 4 h post-LPS. Animals administered with these mAbs 2 h after LPS treatment are sacrificed 24 h post-LPS[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
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Keywords:

Arg-Gly-Glu-Ser(TFA)OthersInhibitorinhibitorinhibit

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Product name:
Arg-Gly-Glu-Ser(TFA)
Cat. No.:
HY-P0309A
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