1. GPCR/G Protein
    Neuronal Signaling
  2. Neuropeptide Y Receptor
  3. BIBP3226 TFA

BIBP3226 TFA 

Cat. No.: HY-107726
Handling Instructions

BIBP3226 TFA is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 TFA displays anxiogenic-like effect.

For research use only. We do not sell to patients.

BIBP3226 TFA Chemical Structure

BIBP3226 TFA Chemical Structure

CAS No. : 1068148-47-9

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Description

BIBP3226 TFA is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 TFA displays anxiogenic-like effect[1][2].

In Vivo

BIBP3226 (0.5, 5μg; i.c.v.) induces an anxiogenic-like effect at the higher dose[1].

Animal Model: Male Wistar rats 270-350 g[1]
Dosage: 0.5, 5μg
Administration: I.c.v
Result: At the dose of 5μg caused an anxiogenic-like effect while the lower dose was ineffective.
Molecular Weight

587.59

Formula

C₂₉H₃₂F₃N₅O₅

CAS No.

1068148-47-9

SMILES

FC(C(O)=O)(F)F.OC(C=C1)=CC=C1CNC([[email protected]@H](CCCNC(N)=N)NC(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

BIBP3226BIBP 3226BIBP-3226Neuropeptide Y ReceptorNPY receptoranxiogenic-likeanxietybehaviorNPFFneuropeptideemotionalprocessesInhibitorinhibitorinhibit

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BIBP3226 TFA
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