1. Metabolic Enzyme/Protease
  2. NADPH Oxidase
  3. NoxA1ds TFA

NoxA1ds TFA 

Cat. No.: HY-P1435A
Handling Instructions

NoxA1ds TFA is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50=20 nM). NoxA1ds TFA exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. NoxA1ds TFA inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. NoxA1ds TFA attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

NoxA1ds TFA Chemical Structure

NoxA1ds TFA Chemical Structure

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Description

NoxA1ds TFA is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50=20 nM). NoxA1ds TFA exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. NoxA1ds TFA inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. NoxA1ds TFA attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro.

Molecular Weight

1239.35

Formula

C₅₂H₈₉F₃N₁₄O₁₇

Sequence

Glu-Pro-Val-Asp-Ala-Leu-Gly-Lys-Ala-Lys-Val-NH2

Sequence Shortening

EPVDALGKAKV-NH2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

NoxA1dsNADPH OxidaseNOXInhibitorinhibitorinhibit

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NoxA1ds TFA
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