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  2. Fibronectin Adhesion-promoting Peptide TFA

Fibronectin Adhesion-promoting Peptide TFA (Synonyms: Heparin Binding Peptide TFA)

Cat. No.: HY-P0306A
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Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. It promotes assembly of mesenchymal stem cell (MSC) spheroids into larger aggregates. Fibronectin Adhesion-promoting Peptide directly promotes the adhesion, spreading, and migration of endothelial cells by reacting with heparin binding domains of cells.

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Fibronectin Adhesion-promoting Peptide TFA Chemical Structure

Fibronectin Adhesion-promoting Peptide TFA Chemical Structure

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Description

Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. It promotes assembly of mesenchymal stem cell (MSC) spheroids into larger aggregates. Fibronectin Adhesion-promoting Peptide directly promotes the adhesion, spreading, and migration of endothelial cells by reacting with heparin binding domains of cells[1][2][3].

In Vitro

GRGDS and Fibronectin Adhesion-promoting Peptide TFA (Heparin Binding Peptide TFA: WQPPRARI) micropatterns increase the endothelialisation of prosthetic materials in vitro. Fibronectin Adhesion-promoting Peptide also enhances haptotactic cell migration. The anti-apoptotic effects of fibronectin require the presence of the WQPPRARI sequence, which may be due to synergistic survival signals mediated by this sequence and by the RGD motif[1].
RDGS and Fibronectin Adhesion-promoting Peptide TFA promote cell adhesion through different activation pathways that induce different forms of adhesion which can be highlighted through the analysis of focal and fibrillar contacts[2].

Molecular Weight

1137.22

Formula

C₄₉H₇₅F₃N₁₆O₁₂

Sequence

Trp-Gln-Pro-Pro-Arg-Ala-Arg-Ile

Sequence Shortening

WQPPRARI

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Fibronectin Adhesion-promoting PeptideHeparin Binding PeptideOthersassemblyMSCspheroids celladhesionspreadingmigrationheparinbindingdomainsInhibitorinhibitorinhibit

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Fibronectin Adhesion-promoting Peptide TFA
Cat. No.:
HY-P0306A
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