SN-38-CO-DMEDA TFA
Based on 1 Customer Validation
SN-38-CO-DMEDA TFA is the intermediate product for synthesizing antibody-conjugated drug LND1035.
For research use only. We do not sell to patients.
- Purity: 98.44%
- CAS No.: 1224601-17-5
- Formula: C29H31F3N4O8
- Molecular Weight:620.57
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
ADC Intermedia
Chemical Information
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CAS No. 1224601-17-5
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Appearance Solid
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Molecular Weight 620.57
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Formula C29H31F3N4O8
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Color Light yellow to yellow
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SMILES
CCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC=C(OC(N(C)CCNC)=O)C=C51.O=C(O)C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (161.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6114 mL | 8.0571 mL | 16.1142 mL | 40.2855 mL |
| 5 mM | 0.3223 mL | 1.6114 mL | 3.2228 mL | 8.0571 mL | |
| 10 mM | 0.1611 mL | 0.8057 mL | 1.6114 mL | 4.0286 mL | |
| 15 mM | 0.1074 mL | 0.5371 mL | 1.0743 mL | 2.6857 mL | |
| 20 mM | 0.0806 mL | 0.4029 mL | 0.8057 mL | 2.0143 mL | |
| 25 mM | 0.0645 mL | 0.3223 mL | 0.6446 mL | 1.6114 mL | |
| 30 mM | 0.0537 mL | 0.2686 mL | 0.5371 mL | 1.3429 mL | |
| 40 mM | 0.0403 mL | 0.2014 mL | 0.4029 mL | 1.0071 mL | |
| 50 mM | 0.0322 mL | 0.1611 mL | 0.3223 mL | 0.8057 mL | |
| 60 mM | 0.0269 mL | 0.1343 mL | 0.2686 mL | 0.6714 mL | |
| 80 mM | 0.0201 mL | 0.1007 mL | 0.2014 mL | 0.5036 mL | |
| 100 mM | 0.0161 mL | 0.0806 mL | 0.1611 mL | 0.4029 mL |