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Pepinh-TRIF TFA

10 Cited Publications
Customer Review

Based on 10 publication(s) in Google Scholar

Pepinh-TRIF (TFA) is a 30 aa peptide that blocks TIR-domain-containing adapter-inducing interferon-β (TRIF) signaling by interfering with TLR-TRIF interaction.

For research use only. We do not sell to patients.

  • Purity : 99.79%
  • Formula: C177H273N55O40S2.xC2HF3O2
  • Molecular Weight:3875.54 (free base)
  • Storage:

    Sealed storage, away from moisture and light, under nitrogen.

    Powder   -80°C, 2 years , -20°C, 1 year

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

  • Pepinh-TRIF TFA Chemical Structure
    Pepinh-TRIF TFA Chemical Structure
  • Experimental Validation Results for Pepinh-TRIF TFA
  • Experimental Validation Results for Pepinh-TRIF TFA
  • Experimental Validation Results for Pepinh-TRIF TFA
  • Experimental Validation Results for Pepinh-TRIF TFA
  • Experimental Validation Results for Pepinh-TRIF TFA
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Pepinh-TRIF TFA

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Customer Validation & Images
WBCell Proliferation/Viability AssayRT-PCR
  • RT-PCR
  • WB
  • Cell Proliferation/Viability Assay
  • RT-PCR
  • WB

All Toll-like Receptor (TLR) Isoforms

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  • Pepinh-TRIF TFA Chemical Structure
    Pepinh-TRIF TFA Chemical Structure
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  • 1/16

    Pepinh-TRIF TFA purchased from MedChemExpress. Usage Cited in: Adv Funct Mater. 2025 Aug 3.

    Customer Validation
     Gene expression of IFN-β, TNF-α, IL-6, and CCL2 in RAW 264.7 cells incubated with 100 µg/mL M-BSA@PSiNPs or 100 µg/mL M-BSA for 6 h in the presence of 40 µmol/L TJ-M or 20 µmol/L TFA (Pepinh-TRIF TFA), respectively.

  • 1/16

    Pepinh-TRIF TFA purchased from MedChemExpress. Usage Cited in: PeerJ. 2024 Jan 2:12:e16716. [Abstract]

    Customer Validation
     Cells were treated with the TRIF-specific inhibitor Pepinh-TRIF TFA (40 μM). Western blotting was used to detect the expression of TRIF and p-ERK1/2 proteins in the cells of each group.

  • 1/16

    Pepinh-TRIF TFA purchased from MedChemExpress. Usage Cited in: PeerJ. 2024 Jan 2:12:e16716. [Abstract]

    Customer Validation
     Intervention was performed using the TRIF-specific inhibitor Pepinh-TRIF TFA (40 μM). Cell proliferation in each group was assessed using the CCK-8 assay.

  • 1/16

    Pepinh-TRIF TFA purchased from MedChemExpress. Usage Cited in: Vet Microbiol. 2023 Oct:285:109867. [Abstract]

    Customer Validation
     Pepinh-TRIF TFA (5 μM). MyD88 and TRIF mRNA levels were measured by qPCR at 12 h and 24 h post-DTMUV infection.

  • 1/16

    Pepinh-TRIF TFA purchased from MedChemExpress. Usage Cited in: bioRxiv. 2023 Apr 25.

    Customer Validation
     Treatment with Pepinh-TRIF TFA (40 μM) significantly inhibited RIPK3 and MLKL phosphorylation and LDH release during LPS-induced necroptosis in PAMs.

  • Pepinh-TRIF TFA