FTISADTSK-¹³C ₆,¹⁵N₂(TFA)

Name: FTISADTSK- 13 C 6 , 15 N 2 (TFA)
Brand: MedChemExpress
SKU: HY-P3146S
Rating: 4.5 (1 reviews)

Cat. No.: HY-P3146S Purity: 99.02%: FAQs
Data Sheet SDS COA Handling Instructions

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FTISADTSK-¹³C₆,¹⁵N₂ TFA is ¹³C- and ¹⁵N-labeled FTISADTSK (HY-P3146). FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

FTISADTSK-<sup>13</sup>C <sub>6</sub>,<sup>15</sup>N<sub>2</sub>(TFA) Chemical Structure

FTISADTSK-¹³C ₆,¹⁵N₂(TFA) Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 350	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 880	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 1400	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of FTISADTSK-¹³C ₆,¹⁵N₂(TFA):

FTISADTSK Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1091.01

Formula

C₃₈¹³C₆H₆₉F₃N₈¹⁵N₂O₁₈

Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (91.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.9166 mL	4.5829 mL	9.1658 mL
5 mM	0.1833 mL	0.9166 mL	1.8332 mL
10 mM	0.0917 mL	0.4583 mL	0.9166 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.02%

Select Batch:

Data Sheet (273 KB) SDS (252 KB)

COA (250 KB) RP-HPLC (210 KB) MS (73 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. [Content Brief]

[2]. Bults P, et al. LC-MS/MS-Based Monitoring of In Vivo Protein Biotransformation: Quantitative Determination of Trastuzumab and Its Deamidation Products in Human Plasma. Anal Chem. 2016;88(3):1871-1877. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.9166 mL	4.5829 mL	9.1658 mL	22.9145 mL
	5 mM	0.1833 mL	0.9166 mL	1.8332 mL	4.5829 mL
	10 mM	0.0917 mL	0.4583 mL	0.9166 mL	2.2915 mL
	15 mM	0.0611 mL	0.3055 mL	0.6111 mL	1.5276 mL
	20 mM	0.0458 mL	0.2291 mL	0.4583 mL	1.1457 mL
	25 mM	0.0367 mL	0.1833 mL	0.3666 mL	0.9166 mL
	30 mM	0.0306 mL	0.1528 mL	0.3055 mL	0.7638 mL
	40 mM	0.0229 mL	0.1146 mL	0.2291 mL	0.5729 mL
	50 mM	0.0183 mL	0.0917 mL	0.1833 mL	0.4583 mL
	60 mM	0.0153 mL	0.0764 mL	0.1528 mL	0.3819 mL
	80 mM	0.0115 mL	0.0573 mL	0.1146 mL	0.2864 mL