1. Anti-infection
    Stem Cell/Wnt
    JAK/STAT Signaling
  2. Bacterial
    STAT
  3. Golotimod (TFA)

Golotimod (TFA) (Synonyms: SCV 07 (TFA); Gamma-D-glutamyl-L-tryptophan (TFA))

Cat. No.: HY-14743A
Handling Instructions

Golotimod TFA (SCV 07 TFA), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod TFA (SCV 07 TFA) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod TFA (SCV 07 TFA) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2).

For research use only. We do not sell to patients.

Golotimod (TFA) Chemical Structure

Golotimod (TFA) Chemical Structure

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Description

Golotimod TFA (SCV 07 TFA), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod TFA (SCV 07 TFA) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod TFA (SCV 07 TFA) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2)[1][2][3].

IC50 & Target[2]

STAT3

 

Molecular Weight

447.36

Formula

C₁₈H₂₀F₃N₃O₇

SMILES

O=C(CC[[email protected]@](N)(C(O)=O)[H])N[[email protected]]([H])(C(O)=O)CC1=CNC2=C1C=CC=C2.OC(C(F)(F)F)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Golotimod (TFA)
Cat. No.:
HY-14743A
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