1. Anti-infection
    Stem Cell/Wnt
    JAK/STAT Signaling
  2. Bacterial
    STAT
  3. Golotimod

Golotimod (Synonyms: SCV 07; Gamma-D-glutamyl-L-tryptophan)

Cat. No.: HY-14743
Handling Instructions

Golotimod (SCV-07), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod (SCV-07) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod (SCV-07) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2).

For research use only. We do not sell to patients.

Golotimod Chemical Structure

Golotimod Chemical Structure

CAS No. : 229305-39-9

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Description

Golotimod (SCV-07), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod (SCV-07) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod (SCV-07) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2)[1][2][3].

IC50 & Target[2]

STAT3

 

Molecular Weight

333.34

Formula

C₁₆H₁₉N₃O₅

CAS No.

229305-39-9

SMILES

O=C(CC[[email protected]@](N)(C(O)=O)[H])N[[email protected]]([H])(C(O)=O)CC1=CNC2=C1C=CC=C2

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Golotimod
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