1. Anti-infection
    Stem Cell/Wnt
    JAK/STAT Signaling
  2. Bacterial
    STAT
  3. Golotimod hydrochloride

Golotimod hydrochloride (Synonyms: SCV 07 hydrochloride; Gamma-D-glutamyl-L-tryptophan hydrochloride)

Cat. No.: HY-14743B Purity: 98.90%
Handling Instructions

Golotimod hydrochloride (SCV 07 hydrochloride), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod hydrochloride (SCV 07 hydrochloride) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod hydrochloride (SCV 07 hydrochloride) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2).

For research use only. We do not sell to patients.

Golotimod hydrochloride Chemical Structure

Golotimod hydrochloride Chemical Structure

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 385 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 550 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2250 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Golotimod hydrochloride (SCV 07 hydrochloride), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod hydrochloride (SCV 07 hydrochloride) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod hydrochloride (SCV 07 hydrochloride) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2)[1][2][3].

IC50 & Target

STAT3

 

Molecular Weight

369.80

Formula

C₁₆H₂₀ClN₃O₅

SMILES

O=C(CC[[email protected]@](N)(C(O)=O)[H])NC([H])(C(O)=O)CC1=CNC2=C1C=CC=C2.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (338.02 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7042 mL 13.5208 mL 27.0416 mL
5 mM 0.5408 mL 2.7042 mL 5.4083 mL
10 mM 0.2704 mL 1.3521 mL 2.7042 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

GolotimodSCV 07Gamma-D-glutamyl-L-tryptophanSCV07SCV-07BacterialSTATInhibitorinhibitorinhibit

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Product name:
Golotimod hydrochloride
Cat. No.:
HY-14743B
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