TLR7/8 agonist 4 TFA
TLR7/8 agonist 4 TFA (compound 41) is a potent TLR7/8 agonist. TLR7/8 agonist 4 TFA has anti-cancer activity.
For research use only. We do not sell to patients.
- CAS No.: 2388520-34-9
- Formula: C20H25F3N6O2
- Molecular Weight:438.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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TLR7 |
TLR8 |
Tumor growth is invariably accompanied by the acquisition of mutations that facilitate escape from immune surveillance. Nevertheless, the process of tumorigenesis leads to the accumulation of mutated antigens-specifically, neoantigens-which, following ex vivo stimulation, are readily recognized by the host immune system. Consequently, delivering these neoantigens to activated dendritic cells via antibody-tumor immune complexes offers a means to overcome the immune system's state of "immune ignorance" toward the tumor. Indeed, the simultaneous delivery of tumor-binding antibodies and dendritic cell adjuvants via intratumoral injection has successfully induced potent anti-tumor immune responses. Thus, dendritic cell adjuvants-such as Toll-like receptor agonists-represent a key potential strategy in the fight against cancer[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2388520-34-9
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Molecular Weight 438.45
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Formula C20H25F3N6O2
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SMILES
O=C(O)C(F)(F)F.NC1=NC2=CC=C(N3CCNCC3)C=C2C4=C1NC(CCCC)=N4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TLR7/8 agonist 4 TFA Related Classifications
HY-139017A Related Classifications
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