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Succinic acid-d<sub>6</sub>

" in MedChemExpress (MCE) Product Catalog:

3139

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12

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33

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1

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15

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10

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3035

Isotope-Labeled Compounds

3

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15

Click Chemistry

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0420S
    Succinic acid-d6

    Wormwood acid-d<sub>6sub>

    		 Endogenous Metabolite Metabolic Disease
    Succinic acid-d6 is the deuterium labeled Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism.
    <em>Succinic</em> acid-d<em>6</em>
  • HY-N0420
    Succinic acid
    4 Publications Verification

    Wormwood acid

    		 Endogenous Metabolite Neurological Disease
    Succinic acid is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid is an important platform chemical. Succinic acid can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
    <em>Succinic</em> acid
  • HY-W441002
    DSPE-succinic acid

    		Liposome Others
    DSPE-succinic acid is a phophalipid capped with a carboxylic acid moiety. The carboxylic acid moiety is reactive with amine to from a stable amide linkage. DSPE-succinic acid can be used to prepare nanoparticles or liposomes for agent nanocarrier to deliver therapeutics .
    DSPE-<em>succinic</em> acid
  • HY-146227
    DNA topoisomerase II inhibitor 1

    		Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-RS13999
    SUB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-100560S
    Abscisic acid-d6

    (S)​-​(+)​-​Abscisic acid-d<sub>6sub>; ABA-d<sub>6sub>

    		 Proton Pump Metabolic Disease
    Abscisic acid-d6 is deuterium labeled Abscisic acid. Abscisic acid inhibits proton pump (H+-ATPase)[1].
    Abscisic acid-d<em>6</em>
  • HY-W396714
    Succinic acid sodium

    Wormwood acid sodium

    		 Potassium Channel TET Protein Neurological Disease
    Succinic acid sodium is a potent and orally active anxiolytic agent. Succinic acid sodium shows inhibitory effects on colonic epithelial cell proliferation in vivo. Succinic acid sodium can down-regulate the expression of KCNMB1 (potassium channel subunit β1) and TET1 (ten‑eleven translocation 1). Succinic acid sodium can be used for gestational hypertension research .
    <em>Succinic</em> acid sodium
  • HY-N0593S2
    Deoxycholic acid-d6

    Cholanoic acid-d<sub>6sub>; Desoxycholic acid-d<sub>6sub>

    		 Isotope-Labeled Compounds G protein-coupled Bile Acid Receptor 1 Endogenous Metabolite Metabolic Disease
    Deoxycholic acid-d6 is the deuterium labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
    Deoxycholic acid-d<em>6</em>
  • HY-B0236S
    6-Aminocaproic acid-d6

    EACA-d<sub>6sub>; Epsilon-Amino-n-caproic acid-d<sub>6sub>; 6-Aminohexanoic acid-d<sub>6sub>

    		 Isotope-Labeled Compounds Metabolic Disease
    6-Aminocaproic acid-d6 is deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1][2].
    <em>6</em>-Aminocaproic acid-d<em>6</em>
  • HY-N0420S2
    Succinic acid-13C4

    		Endogenous Metabolite Neurological Disease
    Succinic acid- 13C4 is the 13C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].
    <em>Succinic</em> acid-13C4
  • HY-N0420S4
    Succinic acid-13C2

    		Endogenous Metabolite Neurological Disease
    Succinic acid- 13C2 is the 13C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].
    <em>Succinic</em> acid-13C2
  • HY-B1350S
    Fusidic acid-d6

    Fusidate-d<sub>6sub>; SQ-16603-d<sub>6sub>

    		 Bacterial Antibiotic Infection
    Fusidic acid-d6 is the deuterium labeled Fusidic acid. Fusidic acid (Fusidate) a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid has no corticosteroid effects. Fusidic acid inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome[1][2].
    Fusidic acid-d<em>6</em>
  • HY-79369S
    Succinic anhydride-d4

    		Isotope-Labeled Compounds ADC Linker Cancer
    Succinic anhydride-d4 is the deuterium labeled Succinic anhydride. Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide[1].
    <em>Succinic</em> anhydride-d4
  • HY-N0420A
    Succinic acid tromethamine

    Wormwood acid tromethamine

    		 Endogenous Metabolite Neurological Disease
    Succinic acid tromethamine is a potent and orally active anxiolytic agent. Succinic acid tromethamine is an intermediate product of the tricarboxylic acid cycle. Succinic acid tromethamine can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries .
    <em>Succinic</em> acid tromethamine
  • HY-N0610AS
    Cinnamic acid-d6

    3-Phenylacrylic acid-d<sub>6sub>; β-Phenylacrylic acid-d<sub>6sub>

    		 Endogenous Metabolite Cancer
    Cinnamic acid-d6 is the deuterium labeled Cinnamic acid. Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.
    Cinnamic acid-d<em>6</em>
  • HY-79369
    Succinic anhydride

    		ADC Linker Cancer
    Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide .
    <em>Succinic</em> anhydride
  • HY-N0420S1
    Succinic-2,2,3,3-d4 acid

    		Endogenous Metabolite Metabolic Disease
    Succinic-2,2,3,3-d4 acid is the deuterium labeled Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism.
    <em>Succinic</em>-2,2,3,3-d4 acid
  • HY-12222S
    Obeticholic acid-d5

    INT-747-d<sub>5sub>; 6-ECDCA-d<sub>5sub>; 6-Ethylchenodeoxycholic acid-d<sub>5sub>

    		 FXR Autophagy Others
    Obeticholic acid-d5 is the deuterium labeled Obeticholic acid. Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy[1][2][3].
    Obeticholic acid-d5
  • HY-79369S1
    Succinic anhydride-13C2

    		ADC Linker Cancer
    Succinic anhydride- 13C2 is the 13C labeled Succinic anhydride[1]. Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide[2].
    <em>Succinic</em> anhydride-13C2
  • HY-14649S3
    Retinoic acid-d6

    Vitamin A acid-d<sub>6sub>; all-trans-Retinoic acid-d<sub>6sub>; ATRA-d<sub>6sub>

    		 RAR/RXR PPAR Autophagy Endogenous Metabolite Cancer
    Retinoic acid-d6 is the deuterium labeled Retinoic acid[1]. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[2][3][4][5][6][7].
    Retinoic acid-d<em>6</em>
  • HY-10585S1
    Valproic acid-d6

    VPA-d<sub>6sub>; 2-Propylpentanoic acid-d<sub>6sub>

    		 HDAC Autophagy Mitophagy HIV Notch Endogenous Metabolite Cancer
    Valproic acid-d6 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches[1][2].
    Valproic acid-d<em>6</em>
  • HY-10844S1
    Pretomanid-d5

    PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>

    		 Antibiotic Bacterial Isotope-Labeled Compounds Infection Cancer
    Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d5
  • HY-145942
    Octenyl succinic anhydride

    		Biochemical Assay Reagents Inflammation/Immunology
    Octenyl succinic anhydride can be used to esterify Starch to yield a hydrocolloid with amphiphilic properties, octenyl succinylated starch (OS-starch). Octenyl succinic anhydride (OSA) modification affects interaction between molecules on the outer surfaces of two starch granules by altering molecular structures on the outer surfaces .
    Octenyl <em>succinic</em> anhydride
  • HY-101108S
    Tazarotenic acid-d6

    AGN 190299-d<sub>6sub>

    		 Isotope-Labeled Compounds Drug Metabolite Others
    Tazarotenic acid-d6 is deuterium labeled Tazarotenic acid. Tazarotenic acid is the metabolite of Tazarotene. Tazarotenic acid binding to retinoic acid receptors (RARs) is the probable molecular target of retinoid action. Tazarotenic acid has the potential for the research of warty dyskeratoma .
    Tazarotenic acid-d<em>6</em>
  • HY-B0167S
    Salicylic acid-d6

    2-Hydroxybenzoic acid-d<sub>6sub>

    		 COX Autophagy Mitophagy Apoptosis Inflammation/Immunology Cancer
    Salicylic acid-d6 is a deuterium labeled Salicylic acid. Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation[1].
    Salicylic acid-d<em>6</em>
  • HY-B0236S1
    6-Aminocaproic acid-d10

    EACA-d<sub>10sub>; Epsilon-Amino-n-caproic acid-d<sub>10sub>; 6-Aminohexanoic acid-d<sub>10sub>

    		 Isotope-Labeled Compounds Metabolic Disease
    6-Aminocaproic acid-d10 is the deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1][2].
    <em>6</em>-Aminocaproic acid-d10
  • HY-70002BS
    Enzalutamide carboxylic acid-d6

    MDV3100 carboxylic acid-d<sub>6sub>

    		 Autophagy Androgen Receptor Isotope-Labeled Compounds Cancer
    Enzalutamide carboxylic acid-d6 is the deuterium labeled Enzalutamide carboxylic acid (MDV3100 carboxylic acid). Enzalutamide carboxylic acid is an inactive metabolite of Enzalutamide[1].
    Enzalutamide carboxylic acid-d<em>6</em>
  • HY-A0143S
    Dihomo-γ-linolenic acid-d6

    DGLA-d<sub>6sub>; all-cis-8,11,14-Eicosatrienoic acid-d<sub>6sub>

    		 Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology Cancer
    Dihomo-γ-linolenic acid-d6 (DGLA-d6) is the deuterium labeled Dihomo-γ-linolenic acid. Dihomo-γ-linolenic acid (all-cis-8,11,14-Eicosatrienoic acid) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system[1][2][3].
    Dihomo-γ-linolenic acid-d<em>6</em>
  • HY-12771S2
    O-Desmethyl Mebeverine acid-d6

    Mebeverine metabolite O-desmethyl Mebeverine acid-d<sub>6sub>

    		 Isotope-Labeled Compounds Drug Metabolite Neurological Disease
    O-Desmethyl Mebeverine acid-d6 is deuterium labeled O-desmethyl Mebeverine acid.
    O-Desmethyl Mebeverine acid-d<em>6</em>
  • HY-108398AS
    Mead acid-d6

    5,8,11-Eicosatrienoic acid-d<sub>6sub>

    		 Isotope-Labeled Compounds Metabolic Disease Cancer
    Mead acid-d6 is the deuterium labeled Mead acid. Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency[1].
    Mead acid-d<em>6</em>
  • HY-N0351S1
    p-Coumaric acid-d6

    trans-4-Hydroxycinnamic acid-d<sub>6sub>

    		 Endogenous Metabolite Cancer
    p-Coumaric acid-d6 is the deuterium labeled p-Coumaric acid (HY-N0351). p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities[1][2].
    p-Coumaric acid-d<em>6</em>
  • HY-B0715S
    Pentoxifylline-d6

    BL-191-d<sub>6sub>; PTX-d<sub>6sub>; Oxpentifylline-d<sub>6sub>

    		 Phosphodiesterase (PDE) Autophagy HIV Cardiovascular Disease Cancer
    Pentoxifylline-d6 is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].
    Pentoxifylline-d<em>6</em>
  • HY-15494S1
    Picropodophyllin-d6

    AXL1717-d<sub>6sub>; Picropodophyllotoxin-d<sub>6sub>; PPP-d<sub>6sub>

    		 Isotope-Labeled Compounds IGF-1R Apoptosis Endocrinology Cancer
    Picropodophyllin-d6 (AXL1717-d6) is deuterium labeled Picropodophyllin. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.
    Picropodophyllin-d<em>6</em>
  • HY-B1873S
    Methoxychlor-d6

    DMDT-d<sub>6sub>; Methoxcide-d<sub>6sub>; Methoxy-DDT-d<sub>6sub>

    		 Isotope-Labeled Compounds Others
    Methoxychlor-d6 is the deuterium labeled Methoxychlor[1].
    Methoxychlor-d<em>6</em>
  • HY-W056964S
    Naphthalene-2,6-dicarboxylic acid-d6

    Naphthalene-2,6-dicarboxylate-d<sub>6sub>

    		 Isotope-Labeled Compounds Others
    Naphthalene-2,6-dicarboxylic acid-d6 is the deuterium labeled Naphthalene-2,6-dicarboxylic acid[1].
    Naphthalene-2,<em>6</em>-dicarboxylic acid-d<em>6</em>
  • HY-119695AS
    Simvastatin acid-d6 ammonium

    Tenivastatin-d<sub>6sub> ammonium

    		 Isotope-Labeled Compounds Endogenous Metabolite Cardiovascular Disease
    Simvastatin acid-d6 (ammonium)mis the deuterium labeled Simvastatin acid ammonium. Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1].
    Simvastatin acid-d<em>6</em> ammonium
  • HY-76542S
    Vitamin D2-d6

    Ergocalciferol-d<sub>6sub>; Calciferol-d<sub>6sub>; Ercalciol-d<sub>6sub>

    		 VD/VDR Endogenous Metabolite Metabolic Disease
    Vitamin D2-d6 is the deuterium labeled Vitamin D2. Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D[1][2].
    Vitamin D2-d<em>6</em>
  • HY-N0537S9
    Xylose-d6

    D-(+)-Xylose-d<sub>6sub>; (+)-Xylose-d<sub>6sub>; Wood sugar-d<sub>6sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    Xylose-d6 is the deuterium labeled Xylose.
    Xylose-d<em>6</em>
  • HY-N1214S
    Squalene-d6

    Super Squalene-d<sub>6sub>; trans-Squalene-d<sub>6sub>; AddaVax-d<sub>6sub>

    		 Isotope-Labeled Compounds Others
    Squalene-d6 is a deuterium labeled Squalene. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .
    Squalene-d<em>6</em>
  • HY-N0067S
    γ-Aminobutyric acid-d6

    4-Aminobutyric acid-d<sub>6sub>

    		 GABA Receptor Endogenous Metabolite Neurological Disease
    γ-Aminobutyric acid-d6 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].
    γ-Aminobutyric acid-d<em>6</em>
  • HY-41681S
    6-Chloro-1-hexanol-d6

    1-Chloro-6-hexanol-d<sub>6sub>; 1-Chloro-6-hydroxyhexane-d<sub>6sub>; 6-Chlorohexanol-d<sub>6sub>

    		 Isotope-Labeled Compounds Others
    6-Chloro-1-hexanol-d6 is the deuterium labeled 6-Chloro-1-hexanol[1].
    <em>6</em>-Chloro-1-hexanol-d<em>6</em>
  • HY-12008S
    Erlotinib-d6 hydrochloride

    CP-358774-d<sub>6sub> hydrochloride; NSC 718781-d<sub>6sub> hydrochloride; OSI-774-d<sub>6sub> hydrochloride

    		 EGFR Autophagy Cancer
    Erlotinib-d6 (hydrochloride) a deuterium labeled Erlotinib Hydrochloride. Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM[1]. Erlotinib-d6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Erlotinib-d<em>6</em> hydrochloride
  • HY-50896S
    Erlotinib-d6

    CP-358774-d<sub>6sub>; NSC 718781-d<sub>6sub>; OSI-774-d<sub>6sub>

    		 EGFR Cancer
    Erlotinib-d6 (CP-358774 D6) is a deuterium labeled Erlotinib (CP-358774). Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR[1]. Erlotinib-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Erlotinib-d<em>6</em>
  • HY-N0005S
    Curcumin-d6

    Diferuloylmethane-d<sub>6sub>; Natural Yellow 3-d<sub>6sub>; Turmeric yellow-d<sub>6sub>

    		 Keap1-Nrf2 Ferroptosis Autophagy Histone Acetyltransferase Epigenetic Reader Domain Mitophagy Influenza Virus Infection Metabolic Disease Inflammation/Immunology
    Curcumin-d6is a deuterium labeled Curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin is an inhibitor of p300 histone acetylatransferase (HATs) and also shows inhibitory effects on NF-κB and MAPKs.
    Curcumin-d<em>6</em>
  • HY-12176AS
    Aliskiren-d6 hydrochloride

    CGP 60536-d<sub>6sub> Hydrochloride; CGP60536Bd<sub>6sub> Hydrochloride; SPP 100d<sub>6sub>(Hydrochloride)

    		 Isotope-Labeled Compounds Renin Cardiovascular Disease Cancer
    Aliskiren-d6 (hydrochloride) is is deuterium labeled Aliskiren, which is a direct renin inhibitor.
    Aliskiren-d<em>6</em> hydrochloride
  • HY-13011S1
    Alectinib-d6

    CH5424802-d<sub>6sub>; RO5424802-d<sub>6sub>; AF802-d<sub>6sub>

    		 Isotope-Labeled Compounds Anaplastic lymphoma kinase (ALK) Cancer
    Alectinib-d6 is deuterium labeled Alectinib. Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively[1]. Alectinib demonstrates effective central nervous system (CNS) penetration[2].
    Alectinib-d<em>6</em>
  • HY-100977S
    Dimethoxycurcumin-d6

    DiMC-d<sub>6sub>; CHC 004-d<sub>6sub>; Di-O-methylcurcumin-d<sub>6sub>

    		 Isotope-Labeled Compounds Inflammation/Immunology
    Dimethoxycurcumin-d6 is the deuterium labeled Dimethoxycurcumin (HY-100977). Dimethoxycurcumin is a derivative of Curcumin that has anti-inflammatory and antioxidant activities .
    Dimethoxycurcumin-d<em>6</em>
  • HY-19655S
    Cethromycin-d6

    ABT-773-d<sub>6sub>; Abbott-195773-d<sub>6sub>; A-195773-d<sub>6sub>

    		 Bacterial Isotope-Labeled Compounds Inflammation/Immunology
    Cethromycin-d6 (ABT-773-d6; Abbott-195773-d6; A-195773-d6) is deuterium-labeled Cethromycin (HY-19655) .
    Cethromycin-d<em>6</em>
  • HY-N0113S
    Hordenine-d6

    Ordenina-d<sub>6sub>; Peyocactine-d<sub>6sub>

    		 Isotope-Labeled Compounds Bacterial Antibiotic Infection Cardiovascular Disease
    Hordenine-d6 (Ordenina-d6) is the deuterium labeled Hordenine. Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .
    Hordenine-d<em>6</em>
  • HY-N0283S
    Diacerein-d6

    Diacerhein-d<sub>6sub>; Diacetylrhein-d<sub>6sub>

    		 Interleukin Related Inflammation/Immunology
    Diacerein-d6 is the deuterium labeled Diacerein[1]. Diacerein (Diacerhein), a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases[2].
    Diacerein-d<em>6</em>

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