1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. Oxprenolol-d7 hydrochloride

Oxprenolol-d7 hydrochloride  (Synonyms: Ba 39089-d7)

Cat. No.: HY-B1486S Purity: 98.25%
COA Handling Instructions

Oxprenolol-d7 (hydrochloride) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle[1].

For research use only. We do not sell to patients.

Oxprenolol-d<sub>7</sub> hydrochloride Chemical Structure

Oxprenolol-d7 hydrochloride Chemical Structure

CAS No. : 1189649-47-5

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1 mg USD 673 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Oxprenolol-d7 (hydrochloride) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

308.85

Formula

C15H17D7ClNO3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])NCC(O)COC1=C(C=CC=C1)OCC=C.Cl[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (323.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2378 mL 16.1891 mL 32.3782 mL
5 mM 0.6476 mL 3.2378 mL 6.4756 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2378 mL 16.1891 mL 32.3782 mL 80.9454 mL
5 mM 0.6476 mL 3.2378 mL 6.4756 mL 16.1891 mL
10 mM 0.3238 mL 1.6189 mL 3.2378 mL 8.0945 mL
15 mM 0.2159 mL 1.0793 mL 2.1585 mL 5.3964 mL
20 mM 0.1619 mL 0.8095 mL 1.6189 mL 4.0473 mL
25 mM 0.1295 mL 0.6476 mL 1.2951 mL 3.2378 mL
30 mM 0.1079 mL 0.5396 mL 1.0793 mL 2.6982 mL
40 mM 0.0809 mL 0.4047 mL 0.8095 mL 2.0236 mL
50 mM 0.0648 mL 0.3238 mL 0.6476 mL 1.6189 mL
60 mM 0.0540 mL 0.2698 mL 0.5396 mL 1.3491 mL
80 mM 0.0405 mL 0.2024 mL 0.4047 mL 1.0118 mL
100 mM 0.0324 mL 0.1619 mL 0.3238 mL 0.8095 mL
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Oxprenolol-d7 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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