1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d82
Based on 1 Customer Validation
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d82 is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for
For research use only. We do not sell to patients.
- Purity : 99%
- CAS No.: 2260669-94-9
- Formula: C42D82NO8P
- Molecular Weight:842.58
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2260669-94-9
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Unlabeled CAS 26853-31-6
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Appearance Solid
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Molecular Weight 842.58
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Formula C42D82NO8P
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Color White to off-white
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SMILES
[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])/C([2H])=C([2H])\C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C(O[C@@](C([2H])([2H])OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)([2H])C([2H])([2H])OP(OC([2H])([2H])C([2H])([2H])[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])([O-])=O)=O
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Synonyms
POPC-d82
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (118.68 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (587 KB)
- English - EN (587 KB)
- Français - FR (587 KB)
- Deutsch - DE (587 KB)
- Norwegian - NO (587 KB)
- Español - ES (587 KB)
- Swedish - SV (587 KB)
- Italian - IT (587 KB)
- Korean - KR (587 KB)
- Portuguese - PT (587 KB)
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Handling Instructions (2659 KB)
References
[1]. Moreno MJ, et al. Translocation of phospholipids and dithionite permeability in liquid-ordered and liquid-disordered membranes. Biophys J. 2006 Aug 1;91(3):873-81. [Content Brief]
[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1868 mL | 5.9342 mL | 11.8683 mL | 29.6708 mL |
| 5 mM | 0.2374 mL | 1.1868 mL | 2.3737 mL | 5.9342 mL | |
| 10 mM | 0.1187 mL | 0.5934 mL | 1.1868 mL | 2.9671 mL | |
| 15 mM | 0.0791 mL | 0.3956 mL | 0.7912 mL | 1.9781 mL | |
| 20 mM | 0.0593 mL | 0.2967 mL | 0.5934 mL | 1.4835 mL | |
| 25 mM | 0.0475 mL | 0.2374 mL | 0.4747 mL | 1.1868 mL | |
| 30 mM | 0.0396 mL | 0.1978 mL | 0.3956 mL | 0.9890 mL | |
| 40 mM | 0.0297 mL | 0.1484 mL | 0.2967 mL | 0.7418 mL | |
| 50 mM | 0.0237 mL | 0.1187 mL | 0.2374 mL | 0.5934 mL | |
| 60 mM | 0.0198 mL | 0.0989 mL | 0.1978 mL | 0.4945 mL | |
| 80 mM | 0.0148 mL | 0.0742 mL | 0.1484 mL | 0.3709 mL | |
| 100 mM | 0.0119 mL | 0.0593 mL | 0.1187 mL | 0.2967 mL |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d82 Related Classifications
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