5-Hydroxyindole-3-acetic acid-d5
Based on 1 Customer Validation
5-Hydroxyindole-3-acetic acid-d5 is the deuterium labeled 5-Hydroxyindole-3-acetic acid (HY-W008253). 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.
For research use only. We do not sell to patients.
- Purity: 98.45%
- CAS No.: 81587-11-3
- Formula: C10H4D5NO3
- Molecular Weight:196.21
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 81587-11-3
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Unlabeled Cas 54-16-0
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Appearance Solid
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Molecular Weight 196.21
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Formula C10H4D5NO3
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Color White to light brown
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SMILES
OC1=C([2H])C(C(C([2H])([2H])C(O)=O)=C([2H])N2)=C2C=C1[2H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (509.66 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.0966 mL | 25.4829 mL | 50.9658 mL | 127.4145 mL |
| 5 mM | 1.0193 mL | 5.0966 mL | 10.1932 mL | 25.4829 mL | |
| 10 mM | 0.5097 mL | 2.5483 mL | 5.0966 mL | 12.7415 mL | |
| 15 mM | 0.3398 mL | 1.6989 mL | 3.3977 mL | 8.4943 mL | |
| 20 mM | 0.2548 mL | 1.2741 mL | 2.5483 mL | 6.3707 mL | |
| 25 mM | 0.2039 mL | 1.0193 mL | 2.0386 mL | 5.0966 mL | |
| 30 mM | 0.1699 mL | 0.8494 mL | 1.6989 mL | 4.2472 mL | |
| 40 mM | 0.1274 mL | 0.6371 mL | 1.2741 mL | 3.1854 mL | |
| 50 mM | 0.1019 mL | 0.5097 mL | 1.0193 mL | 2.5483 mL | |
| 60 mM | 0.0849 mL | 0.4247 mL | 0.8494 mL | 2.1236 mL | |
| 80 mM | 0.0637 mL | 0.3185 mL | 0.6371 mL | 1.5927 mL | |
| 100 mM | 0.0510 mL | 0.2548 mL | 0.5097 mL | 1.2741 mL |