1. JAK/STAT Signaling
    Protein Tyrosine Kinase/RTK
    Autophagy
  2. EGFR
    Autophagy
  3. Gefitinib D8

Gefitinib D8 (Synonyms: ZD1839 D8)

Cat. No.: HY-50895S Purity: 98.42%
Handling Instructions

Gefitinib D8 (ZD1839 D8) is a deuterium labeled Gefitinib. Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells.

For research use only. We do not sell to patients.

Gefitinib D8 Chemical Structure

Gefitinib D8 Chemical Structure

CAS No. : 857091-32-8

Size Price Stock Quantity
5 mg USD 550 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Gefitinib D8:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Gefitinib D8 (ZD1839 D8) is a deuterium labeled Gefitinib. Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells[1][2].

IC50 & Target

IC50: 37 nM (Tyr1173 site, in NR6wtEGFR cells), 37 nM (Tyr992 site, in NR6wtEGFR cells)[1]

Molecular Weight

454.95

Formula

C₂₂H₁₆D₈ClFN₄O₃

CAS No.
SMILES

[2H]C1([2H])OC([2H])([2H])C([2H])([2H])N(CCCOC2=CC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=C2OC)C1([2H])[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Gefitinib D8ZD1839 D8Gefitinib D 8Gefitinib D-8EGFRAutophagyEpidermal growth factor receptorErbB-1HER1DeuteriumlabeledGefitinibInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Gefitinib D8
Cat. No.:
HY-50895S
Quantity:
MCE Japan Authorized Agent: