Acetophenone-d8
Based on 1 Customer Validation
Acetophenone-d8 is the deuterium labeled Acetophenone. Acetophenone is an organic compound with simple structure.
For research use only. We do not sell to patients.
- Purity: 99.96%
- CAS No.: 19547-00-3
- Formula: C8D8O
- Molecular Weight:128.20
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 19547-00-3
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Unlabeled Cas 98-86-2
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Appearance Liquid
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Molecular Weight 128.20
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Formula C8D8O
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Color Colorless to light yellow
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SMILES
[2H]C1=C(C(C([2H])([2H])[2H])=O)C([2H])=C([2H])C([2H])=C1[2H]
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Synonyms
1-Phenylethan-1-One-d8
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 200 mg/mL (1560.06 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Żymańczyk-Duda E, et al. Reductive capabilities of different cyanobacterial strains towards acetophenone as a model substrate - Prospect of applications for chiral building blocks synthesis. Bioorg Chem. 2019 Feb 25. pii: S0045-2068(18)31467-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.8003 mL | 39.0016 mL | 78.0031 mL | 195.0078 mL |
| 5 mM | 1.5601 mL | 7.8003 mL | 15.6006 mL | 39.0016 mL | |
| 10 mM | 0.7800 mL | 3.9002 mL | 7.8003 mL | 19.5008 mL | |
| 15 mM | 0.5200 mL | 2.6001 mL | 5.2002 mL | 13.0005 mL | |
| 20 mM | 0.3900 mL | 1.9501 mL | 3.9002 mL | 9.7504 mL | |
| 25 mM | 0.3120 mL | 1.5601 mL | 3.1201 mL | 7.8003 mL | |
| 30 mM | 0.2600 mL | 1.3001 mL | 2.6001 mL | 6.5003 mL | |
| 40 mM | 0.1950 mL | 0.9750 mL | 1.9501 mL | 4.8752 mL | |
| 50 mM | 0.1560 mL | 0.7800 mL | 1.5601 mL | 3.9002 mL | |
| 60 mM | 0.1300 mL | 0.6500 mL | 1.3001 mL | 3.2501 mL | |
| 80 mM | 0.0975 mL | 0.4875 mL | 0.9750 mL | 2.4376 mL | |
| 100 mM | 0.0780 mL | 0.3900 mL | 0.7800 mL | 1.9501 mL |
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