p-Cresol sulfate-d₇ potassium  (Synonyms: p-Tolyl sulfate-d₇ (potassium))

p-Cresol sulfate-d₇ (potassium) is the deuterium labeled p-Cresyl sulfate potassium. p-Methylphenyl potassium sulfate is a prototype protein-bound uremic toxin[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

233.33

C₇D₇KO₄S

2469278-96-2

Solid

White to off-white

O=S(OC1=C([2H])C([2H])=C(C([2H])([2H])[2H])C([2H])=C1[2H])(O[K])=O

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief]

  [2]. Gryp T, et al. p-Cresyl Sulfate. Toxins (Basel). 2017 Jan 29;9(2).  [Content Brief]