1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. (S)-3,4-Dihydroxybutyric acid lithium hydrate

(S)-3,4-Dihydroxybutyric acid lithium hydrate, a normal human urinary metabolite, is a β-oxidation metabolite of γ-hydroxybutyrate. (S)-3,4-Dihydroxybutyric acid lithium hydrate can be used for research on succinic semialdehyde dehydrogenase deficiency.

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(S)-3,4-Dihydroxybutyric acid lithium hydrate

(S)-3,4-Dihydroxybutyric acid lithium hydrate Estructura química

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
En stock
Solution
10 mM * 1 mL in Water En stock
Solid
5 mg En stock
10 mg En stock
25 mg En stock
50 mg   Obtener un presupuesto  
100 mg   Obtener un presupuesto  

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Other Forms of (S)-3,4-Dihydroxybutyric acid lithium hydrate:

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Descripciòn

(S)-3,4-Dihydroxybutyric acid lithium hydrate, a normal human urinary metabolite, is a β-oxidation metabolite of γ-hydroxybutyrate. (S)-3,4-Dihydroxybutyric acid lithium hydrate can be used for research on succinic semialdehyde dehydrogenase deficiency[1][2].

IC50 & Target[1]

Human Endogenous Metabolite

 

In Vitro

(S)-3,4-Dihydroxybutyric acid lithium hydrate is excreted in increased concentration in patients‘s urine with succinic semialdehyde dehydrogenase (SSADH) deficiency[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

144.05

Fòrmula

C4H9LiO5

Appearance

Solid

Color

White to off-white

SMILES

O=C([O-])C[C@H](O)CO.[Li+].[x].[y].O

Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad
In Vitro: 

H2O : 125 mg/mL (867.75 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.9420 mL 34.7102 mL 69.4203 mL
5 mM 1.3884 mL 6.9420 mL 13.8841 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (694.20 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureza y Documentación

Purity: 98.1%

Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 6.9420 mL 34.7102 mL 69.4203 mL 173.5508 mL
5 mM 1.3884 mL 6.9420 mL 13.8841 mL 34.7102 mL
10 mM 0.6942 mL 3.4710 mL 6.9420 mL 17.3551 mL
15 mM 0.4628 mL 2.3140 mL 4.6280 mL 11.5701 mL
20 mM 0.3471 mL 1.7355 mL 3.4710 mL 8.6775 mL
25 mM 0.2777 mL 1.3884 mL 2.7768 mL 6.9420 mL
30 mM 0.2314 mL 1.1570 mL 2.3140 mL 5.7850 mL
40 mM 0.1736 mL 0.8678 mL 1.7355 mL 4.3388 mL
50 mM 0.1388 mL 0.6942 mL 1.3884 mL 3.4710 mL
60 mM 0.1157 mL 0.5785 mL 1.1570 mL 2.8925 mL
80 mM 0.0868 mL 0.4339 mL 0.8678 mL 2.1694 mL
100 mM 0.0694 mL 0.3471 mL 0.6942 mL 1.7355 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Inquiry Information

Nombre del producto:
(S)-3,4-Dihydroxybutyric acid lithium hydrate
Cat. No.:
HY-113304A
Cantidad:
MCE Japan Authorized Agent: