(S)-3,4-Dihydroxybutyric acid lithium hydrate

Name: (S)-3,4-Dihydroxybutyric acid lithium hydrate
Brand: MedChemExpress
SKU: HY-113304A
Rating: 4.5 (1 reviews)

Cat. No.: HY-113304A Purity: ≥95.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

(S)-3,4-Dihydroxybutyric acid (lithium hydrate) is a normal human urinary metabolite that is excreted in increased concentration in patients with succinic semialdehyde dehydrogenase (SSADH) deficiency.

For research use only. We do not sell to patients.

(S)-3,4-Dihydroxybutyric acid lithium hydrate Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 240	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 480	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (S)-3,4-Dihydroxybutyric acid lithium hydrate:

(S)-3,4-Dihydroxybutyric acid Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

Microbial Metabolite

Human Endogenous Metabolite

Molecular Weight

144.05

Formula

C₄H₉LiO₅

Appearance

Solid

Color

White to off-white

SMILES

O=C([O-])C[C@H](O)CO.[Li+].[x].[y].O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 125 mg/mL (867.75 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.9420 mL	34.7102 mL	69.4203 mL
5 mM	1.3884 mL	6.9420 mL	13.8841 mL
10 mM	0.6942 mL	3.4710 mL	6.9420 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (694.20 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (269 KB) SDS (0 KB)

COA (244 KB) HNMR (247 KB)

Handling Instructions (2659 KB)

References

[1]. Shinka T, et al. Rapid and sensitive detection of urinary 4-hydroxybutyric acid and its related compounds by gas chromatography-mass spectrometry in a patient with succinic semialdehyde dehydrogenase deficiency. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Aug 25;776(1):57-63. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.9420 mL	34.7102 mL	69.4203 mL	173.5508 mL
	5 mM	1.3884 mL	6.9420 mL	13.8841 mL	34.7102 mL
	10 mM	0.6942 mL	3.4710 mL	6.9420 mL	17.3551 mL
	15 mM	0.4628 mL	2.3140 mL	4.6280 mL	11.5701 mL
	20 mM	0.3471 mL	1.7355 mL	3.4710 mL	8.6775 mL
	25 mM	0.2777 mL	1.3884 mL	2.7768 mL	6.9420 mL
	30 mM	0.2314 mL	1.1570 mL	2.3140 mL	5.7850 mL
	40 mM	0.1736 mL	0.8678 mL	1.7355 mL	4.3388 mL
	50 mM	0.1388 mL	0.6942 mL	1.3884 mL	3.4710 mL
	60 mM	0.1157 mL	0.5785 mL	1.1570 mL	2.8925 mL
	80 mM	0.0868 mL	0.4339 mL	0.8678 mL	2.1694 mL
	100 mM	0.0694 mL	0.3471 mL	0.6942 mL	1.7355 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.