2. Anti-infection
  3. Bacterial Antibiotic
  4. Ceftriaxone-d3 disodium

Ceftriaxone-d3 disodium  (Synonyms: Ro 13-9904-d3 disodium)

Cat. No.: HY-B0712S
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Ceftriaxone-d3 (disodium) is the deuterium labeled Ceftriaxone. Ceftriaxone is a third-generation cephalosporin antibiotic with excellent activity against many gram-negative, and reasonable activity against most gram-positive microorganisms. Anti-inflammatory and antioxidant characteristics[1][2].

For research use only. We do not sell to patients.

Ceftriaxone-d<sub>3</sub> disodium Chemical Structure

Ceftriaxone-d3 disodium Chemical Structure

CAS No. : 1132650-38-4

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Based on 1 publication(s) in Google Scholar

Other Forms of Ceftriaxone-d3 disodium:

Ceftriaxone-d3 disodium Related Antibodies

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Description

Ceftriaxone-d3 (disodium) is the deuterium labeled Ceftriaxone. Ceftriaxone is a third-generation cephalosporin antibiotic with excellent activity against many gram-negative, and reasonable activity against most gram-positive microorganisms. Anti-inflammatory and antioxidant characteristics[1][2].

IC50 & Target

β-lactam

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ceftriaxone-d3 disodium Related Antibodies
Molecular Weight

602.57

Formula

C18H14D3N8Na2O7S3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=C(CSC(N(NC2=O)C)=NC2=O)CS[C@@]([C@@H]3NC(/C(C4=CSC(N)=N4)=N\OC([2H])([2H])[2H])=O)([H])N1C3=O)O[Na].[Na]
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 31.25 mg/mL (51.86 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6596 mL 8.2978 mL 16.5956 mL
5 mM 0.3319 mL 1.6596 mL 3.3191 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6596 mL 8.2978 mL 16.5956 mL 41.4890 mL
5 mM 0.3319 mL 1.6596 mL 3.3191 mL 8.2978 mL
10 mM 0.1660 mL 0.8298 mL 1.6596 mL 4.1489 mL
15 mM 0.1106 mL 0.5532 mL 1.1064 mL 2.7659 mL
20 mM 0.0830 mL 0.4149 mL 0.8298 mL 2.0744 mL
25 mM 0.0664 mL 0.3319 mL 0.6638 mL 1.6596 mL
30 mM 0.0553 mL 0.2766 mL 0.5532 mL 1.3830 mL
40 mM 0.0415 mL 0.2074 mL 0.4149 mL 1.0372 mL
50 mM 0.0332 mL 0.1660 mL 0.3319 mL 0.8298 mL
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Ceftriaxone-d3 disodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ceftriaxone-d3 disodium1132650-38-4Ro 13-9904-d3 disodiumBacterialAntibioticInhibitorinhibitorinhibit

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