1-Naphthol-d8
1-Naphthol-d8 is the deuterium labeled 1-Naphthol. 1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe.
For research use only. We do not sell to patients.
- CAS No.: 207569-03-7
- Formula: C10D8O
- Molecular Weight:152.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 207569-03-7
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Molecular Weight 152.22
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Formula C10D8O
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SMILES
[2H]C1=C(C2=C(C([2H])=C([2H])C([2H])=C2[2H])C([2H])=C1[2H])O[2H]
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Synonyms
Furro ER-d8; NSC 9586-d8; Nako TRB-d8
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Swain J, et al. 1-Naphthol as an ESPT fluorescent molecular probe for sensing thermotropic microenvironmental changes of pluronic F127 in aqueous media. Phys Chem Chem Phys. 2015 Jul 14;17(26):16752-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)