Blonanserin-d5
Based on 1 Customer Validation
Blonanserin-d5 (AD-5423-d5) is a deuterium labeled Blonanserin (HY-13575). Blonanserin is a dopamine D2/5-HT2 receptor antagonist and an atypical antipsychotic.
For research use only. We do not sell to patients.
- CAS No.: 1346599-86-7
- Formula: C23H25D5FN3
- Molecular Weight:372.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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5-HT2 Receptor |
D2 Receptor |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1346599-86-7
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Unlabeled Cas 132810-10-7
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Molecular Weight 372.53
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Formula C23H25D5FN3
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SMILES
FC1=CC=C(C2=C(CCCCCC3)C3=NC(N4CCN(C([2H])([2H])C([2H])([2H])[2H])CC4)=C2)C=C1
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Synonyms
AD-5423-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Tenjin, T., et al., Profile of blonanserin for the treatment of schizophrenia. Neuropsychiatr Dis Treat, 2013. 9: p. 587-94. [Content Brief]
[2]. Oka, M., et al., Pharmacological profile of AD-5423, a novel antipsychotic with both potent dopamine-D2 and serotonin-S2 antagonist properties. J Pharmacol Exp Ther, 1993. 264(1): p. 158-65. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)