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Cat. No.: HY-12772S2

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(2R,4S)-Hydroxy Itraconazole-d₅

Name: (2R,4S)-Hydroxy Itraconazole-d5
Brand: MedChemExpress
SKU: HY-12772S2
Price: 1150.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: (2R,4S)-R-63373-d₅)

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(2R,4S)-Hydroxy Itraconazole-d₅ is the deuterium labeled (2R,4S)-Hydroxy Itraconazole.

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CAS No.: 1217524-77-0
Formule: C₃₅H₃₃D₅Cl₂N₈O₅
Masse moléculaire:726.66

Stockage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

(2R,4S)-Hydroxy Itraconazole-d₅ Chemical Structure

CAS No.: 1217524-77-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
- Application
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

(2R,4S)-Hydroxy Itraconazole-d₅ is the deuterium labeled (2R,4S)-Hydroxy Itraconazole^[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1217524-77-0
Unlabeled Cas 112559-91-8
Appearance Solid
Masse moléculaire 726.66
Formule C₃₅H₃₃D₅Cl₂N₈O₅
Color White to off-white
SMILES

O=C(N(N=C1)C(C)([2H])C(O)([2H])C([2H])([2H])[2H])N1C(C=C2)=CC=C2N(CC3)CCN3C(C=C4)=CC=C4OC[C@@H](CO5)O[C@]5(C6=C(C=C(C=C6)Cl)Cl)CN7C=NC=N7
Synonyms

(2R,4S)-R-63373-d₅
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

(2R,4S)-Hydroxy Itraconazole-d₅

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(2R,4S)-Hydroxy Itraconazole-d5

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

(2R,4S)-Hydroxy Itraconazole-d5 Related Classifications

HY-12772S2 Related Classifications

Bioz

(2R,4S)-Hydroxy Itraconazole-d₅

(2R,4S)-Hydroxy Itraconazole-d₅ Related Classifications