Deoxythymidine-5'-triphosphate-13C10 dilithium
Based on 1 Customer Validation
Deoxythymidine-5'-triphosphate-13C10 dilithium (dTTP-13C10 dilithium) is the 13C-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is a deoxyribonucleoside triphosphate and a thymidine analog, which serves as a direct precursor for DNA synthesis. Deoxythymidine-5'-triphosphate can be used for DNA amplification in the DNA polymerase chain reaction (PCR). Deoxythymidine-5'-triphosphate is also applicable to research related to diseases such as leukemia.
For research use only. We do not sell to patients.
- Purity: 99.1%
- Formula: 13C10H15Li2N2O14P3
- Molecular Weight:503.96
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Storage:
Solution, -20°C, 2 years
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 365-08-2
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Appearance Liquid
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Molecular Weight 503.96
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Formula 13C10H15Li2N2O14P3
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Color Colorless to light yellow
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SMILES
O=[13C](N1[13C@H]2[13CH2][13C@H](O)[13C@@H]([13CH2]OP(O)(OP(OP(O)(O[Li])=O)(O[Li])=O)=O)O2)N[13C]([13C]([13CH3])=[13CH]1)=O
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Synonyms
dTTP-13C10 dilithium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Purity & Documentation
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Data Sheet (288 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Tattersall MH, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. European journal of clinical investigation. 1975 Apr;5(2):191-202. [Content Brief]
[2]. Rondan Dueñas JC, et al. Specific requirements for PCR amplification of long mitochondrial A+T-rich DNA. Biotechniques. 1999 Aug;27(2):258-60. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Deoxythymidine-5'-triphosphate-13C10 dilithium Related Classifications
HY-138615S2 Related Classifications
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Keywords
- Deoxythymidine-5'-triphosphate-13C10 dilithium
- dTTP-13C10 dilithium
- Isotope-Labeled Compounds
- DNA/RNA Synthesis
- Nucleoside Antimetabolite/Analog
- Endogenous Metabolite
- chronic granulocytic leukaemia
- acute myeloid leukaemia
- DNA synthesis
- phytohaemagglutinin-stimulated lymphocytes
- leukaemia
- antifolate agents
- nucleated marrow cells
- hydroxyurea
- 5-fluorouracil
- myeloproliferative diseases
- Inhibitor
- inhibitor
- inhibit