Deoxythymidine-5'-triphosphate-15N2,d15 dilithium
Deoxythymidine-5'-triphosphate-15N2,d15 dilithium (dTTP-15N2,d15 dilithium) is the deuterated, 15N-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is a deoxyribonucleoside triphosphate and a thymidine analog, which serves as a direct precursor for DNA synthesis. Deoxythymidine-5'-triphosphate can be used for DNA amplification in the DNA polymerase chain reaction (PCR). Deoxythymidine-5'-triphosphate is also applicable to research related to diseases such as leukemia.
For research use only. We do not sell to patients.
- Formula: C10D15Li215N2O14P3
- Molecular Weight:511.11
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 365-08-2
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Molecular Weight 511.11
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Formula C10D15Li215N2O14P3
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SMILES
O=C([15N]1[C@@]2([2H])C([2H])([2H])[C@@](O[2H])([2H])[C@](C([2H])([2H])OP(O[2H])(OP(OP(O[2H])(O[Li])=O)(O[Li])=O)=O)([2H])O2)[15N]([2H])C(C(C([2H])([2H])[2H])=C1[2H])=O
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Synonyms
dTTP-15N2,d15 dilithium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Tattersall MH, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. European journal of clinical investigation. 1975 Apr;5(2):191-202. [Content Brief]
[2]. Rondan Dueñas JC, et al. Specific requirements for PCR amplification of long mitochondrial A+T-rich DNA. Biotechniques. 1999 Aug;27(2):258-60. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Deoxythymidine-5'-triphosphate-15N2,d15 dilithium
- dTTP-15N2,d15 dilithium
- Isotope-Labeled Compounds
- DNA/RNA Synthesis
- Nucleoside Antimetabolite/Analog
- Endogenous Metabolite
- chronic granulocytic leukaemia
- acute myeloid leukaemia
- DNA synthesis
- phytohaemagglutinin-stimulated lymphocytes
- leukaemia
- antifolate agents
- nucleated marrow cells
- hydroxyurea
- 5-fluorouracil
- myeloproliferative diseases
- Inhibitor
- inhibitor
- inhibit