1. Stem Cell/Wnt
    TGF-beta/Smad
    GPCR/G Protein
    Immunology/Inflammation
  2. TGF-beta/Smad
    CCR
  3. Pirfenidone D5

Pirfenidone D5 (Synonyms: AMR69 D5)

Cat. No.: HY-B0673S
Handling Instructions

Pirfenidone D5 (AMR69 D5) is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities.

For research use only. We do not sell to patients.

Pirfenidone D5 Chemical Structure

Pirfenidone D5 Chemical Structure

CAS No. : 1020719-62-3

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Description

Pirfenidone D5 (AMR69 D5) is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities[1][2][3].

IC50 & Target

TGF-β2[1][2]
CCL2 and CCL12[3]

Molecular Weight

190.25

Formula

C₁₂H₆D₅NO

CAS No.

1020719-62-3

SMILES

O=C1C=CC(C)=CN1C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H]

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Pirfenidone D5AMR69 D5Pirfenidone D 5Pirfenidone D-5TGF-beta/SmadCCRTransforming growth factor betaCC chemokine receptorPirfenidonedeuteriumlabeledantifibroticCCL2CCL12growth-inhibitoryTGF-β2anti-inflammatoryInhibitorinhibitorinhibit

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