Acotiamide-d6 hydrochloride
Acotiamide-d6 (hydrochloride) is deuterium labeled Acotiamide (hydrochloride).
For research use only. We do not sell to patients.
- Formula: C21H25D6ClN4O5S
- Molecular Weight:493.05
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
Unlabeled Cas 185104-11-4
-
Molecular Weight 493.05
-
Formula C21H25D6ClN4O5S
-
SMILES
O=C(C1=CSC(NC(C2=CC(OC([2H])([2H])[2H])=C(OC([2H])([2H])[2H])C=C2O)=O)=N1)NCCN(C(C)C)C(C)C.Cl
-
Synonyms
Z-338-d6 hydrochloride; YM443-d6 hydrochloride
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Nowlan ML, et al. Acotiamide: first global approval. Drugs. 2013 Aug;73(12):1377-83. [Content Brief]
[3]. Attia KAM, et al. Spectrofluorimetric determination of acotiamide hydrochloride trihydrate in the presence of its oxidative degradation product. Luminescence. 2018 Jun;33(4):806-811. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)