Lyso-PAF C-16-d4
Lyso-PAF C-16-d4 (Lyso-platelet-activating factor C-16-d4) is the deuterated-labeled Lyso-PAF C-16 (HY-141570). Lyso-PAF C-16 is a precursor and metabolite of 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (PAF C-16). Lyso-PAF C-16 is a substrate for either PAF C-16 formation by the remodeling pathway or selective acylation with arachidonic acid by a CoA-independent transacylase.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 201216-37-7
- Fòrmula: C24H48D4NO6P
- Peso molecular:485.67
-
Almacenamiento:
Solution, -20°C, 2 years
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
-
HY-114364
UDP-Galactose disodiumP2Y14 Receptor Agonist -
HY-10064S
Ticagrelor-d7Stable Isotope -
HY-50903S
Rivaroxaban-d4Stable Isotope -
HY-109506S
DPPC-d62Stable Isotope -
HY-109506S9
DPPC-13C2Stable Isotope -
HY-N8425
Octacosanoic acidLong-Chain Saturated Fatty Acid -
HY-139931S
1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-PCStable Isotope -
HY-118025
(±)-2-Oxo clopidogrelMetabolites -
HY-15284S
Prasugrel-d5Stable Isotope -
HY-115702S
1-Palmityl-2-O-acetyl-3-glyceryl phosphorylcholine-d4Stable Isotope -
HY-N8425R
Octacosanoic acid (Standard)Reference Standard -
HY-118025R
(±)-2-Oxo clopidogrel (Standard)Metabolites
Ver todos los productos específicos de isoformas Phospholipase
More
Actividad biológica
Descripciòn
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Aplicación
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
No. CAS 201216-37-7
-
Unlabeled CAS 52691-62-0
-
Appearance Liquid
-
Peso molecular 485.67
-
Fòrmula C24H48D4NO6P
-
Color Colorless to light yellow
-
SMILES
CCCCCCCCC([2H])([2H])C([2H])([2H])CCCCCCOC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O
-
Synonyms
Lyso-platelet-activating factor C-16-d4
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Solution, -20°C, 2 years
Pureza y Documentación
-
Ficha de datos (263 KB)
-
SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
-
Instrucciones de manejo (2659 KB)
Referencias
[1]. Grosman N, et al. Similar effects of ether phospholipids, PAF and lyso-PAF on the Ca(2+)-ATPase activity of rat brain synaptosomes and leukocyte membranes. Int Immunopharmacol. 2001;1(7):1321-1329. [Content Brief]
[2]. Uemura Y, et al. A coenzyme A-independent transacylase is linked to the formation of platelet-activating factor (PAF) by generating the lyso-PAF intermediate in the remodeling pathway. J Biol Chem. 1991 May 5;266(13):8268-72. [Content Brief]
[3]. Venable ME, et al. Enzymatic studies of lyso platelet-activating factor acylation in human neutrophils and changes upon stimulation. J Biol Chem. 1993 Apr 15;268(11):7965-75. [Content Brief]
[4]. Yamaura S, et al. Novel enzymatic method for assaying Lp-PLA2 in serum. Clin Chim Acta. 2018 Jun;481:184-188. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lyso-PAF C-16-d4 Related Classifications
HY-141570S Related Classifications
Powered by Bioz
Keywords
- Lyso-PAF C-16-d4
- 201216-37-7
- Lyso-platelet-activating factor C-16-d4
- Isotope-Labeled Compounds
- Phospholipase
- rat brain synaptosomal membranes
- Ca2+-ATPase
- rat mixed peritoneal leukocyte membranes
- rat peritoneal leukocyte membrane
- allergic reactions
- inflammatory reactions
- ether phospholipid derivative
- plasma membrane Ca2+-ATPase
- Inhibitor
- inhibitor
- inhibit