Thiamine-13C3 hydrochloride
Based on 1 Customer Validation
Thiamine-13C3 (hydrochloride) is the 13C-labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
For research use only. We do not sell to patients.
- Purity: 99.9%
- Formula: C913C3H18Cl2N4OS
- Molecular Weight:340.25
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 67-03-8
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Appearance Solid
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Molecular Weight 340.25
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Formula C913C3H18Cl2N4OS
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Color White to light brown
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SMILES
[13CH3][13C]1=[13C](CCO)SC=[N+]1CC2=CN=C(C)N=C2N.[Cl-].Cl
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Synonyms
Thiamine chloride-13C3 hydrochloride; Vitamin B1-13C3 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 100 mg/mL (293.90 mM; Need ultrasonic)
DMSO : 6.67 mg/mL (19.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Moulin M, et al. Analysis of Chlamydomonas thiamin metabolism in vivo reveals riboswitch plasticity. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14622-7. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 2.9390 mL | 14.6951 mL | 29.3902 mL | 73.4754 mL |
| 5 mM | 0.5878 mL | 2.9390 mL | 5.8780 mL | 14.6951 mL | |
| 10 mM | 0.2939 mL | 1.4695 mL | 2.9390 mL | 7.3475 mL | |
| 15 mM | 0.1959 mL | 0.9797 mL | 1.9593 mL | 4.8984 mL | |
| H2O | 20 mM | 0.1470 mL | 0.7348 mL | 1.4695 mL | 3.6738 mL |
| 25 mM | 0.1176 mL | 0.5878 mL | 1.1756 mL | 2.9390 mL | |
| 30 mM | 0.0980 mL | 0.4898 mL | 0.9797 mL | 2.4492 mL | |
| 40 mM | 0.0735 mL | 0.3674 mL | 0.7348 mL | 1.8369 mL | |
| 50 mM | 0.0588 mL | 0.2939 mL | 0.5878 mL | 1.4695 mL | |
| 60 mM | 0.0490 mL | 0.2449 mL | 0.4898 mL | 1.2246 mL | |
| 80 mM | 0.0367 mL | 0.1837 mL | 0.3674 mL | 0.9184 mL | |
| 100 mM | 0.0294 mL | 0.1470 mL | 0.2939 mL | 0.7348 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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